8 completed, 2 withdrawn, 1 terminated. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 8, Withdrawn 2, Terminated 1 |
Follow elbasvir: new trials by email Literature Review of elbasvir trials Research Report on elbasvir
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 Elbasvir/Grazoprevir 50 MG-100 MG Oral Tablet [ZEPATIER] - Hepatitis C Virus Infection, Response to Therapy of | Phase 4 | Withdrawn | University of Maryland, Baltimore | 2019-12-01 | 2020-04-20 | |
| Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier] - Hepatitis C, Hemodialysis | Phase 4 | Completed | University of Pennsylvania | 6 | 2019-09-22 | 2021-12-15 |
| Grazoprevir/Elbasvir for Genotype 1b Chronic Hepatitis C After Liver or Kidney Transplantation grazoprevir 100 mg/ elbasvir 50 mg, Zepatier® - Chronic Hepatitis c, Liver Transplant Infection | Phase 4 | Terminated | Taichung Veterans General Hospital | 14 | 2019-02-14 | 2021-03-16 |
| Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication Elbasvir / Grazoprevir Oral Tablet [Zepatier], Cardiac MRI - Cardiovascular Diseases, Hepatitis C | Phase 4 | Completed | University of Maryland, Baltimore | 87 | 2018-11-18 | 2023-05-22 |
| Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant Combindation treatment with Grazoprevir and Elbasvir fixed dose combination tablet, with or without ribavirin - Cardiac Transplant Disorder, Hepatitis C | Phase 4 | Withdrawn | Raymond T. Chung, MD | 2018-08-01 | 2018-12-20 | |
| Efficacy and Tolerability of Grazoprevir and Elbasvir in Patients With Chronic Genotype 1 HCV and HIV Co-infection grazoprevir and elbasvir - Chronic Hepatitis C | Phase 4 | Completed | Taoyuan General Hospital | 40 | 2017-10-20 | 2018-12-20 |
| HCV Treatment Immune Response With Grazoprevir/Elbasvir Before or After Renal Transplant Post-transplant Grazoprevir and Elbasvir - Hepatitis C, Renal Insufficiency, Chronic | Phase 4 | Completed | University of Maryland, Baltimore | 21 | 2017-05-01 | 2024-04-22 |
| A Study for G1b CHC Patients With CKD-3 Treated With Grazoprevir Plus Elbasvir Grazoprevir plus Elbasvir - Hepatitis C Viral, Chronic Kidney Disease stage3 | Phase 4 | Completed | Kyushu University | 80 | 2017-04-01 | 2019-06-03 |
| Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant elbasvir (50mg) / grazoprevir (100mg) (fixed dose combination) - Renal Failure | Phase 4 | Completed | Massachusetts General Hospital | 8 | 2017-02-01 | 2020-06-09 |
| Exploring Renal Transplants Using Hepatitis C Infected Donors for HCV-negative Recipients Zepatier, Ribavirin, Sofosbuvir - End-Stage Renal Disease, Hepatitis C | Phase 4 | Completed | Johns Hopkins University | 10 | 2016-07-20 | 2018-09-06 |
| Study of Oral Treatments for Hepatitis C SOF/LDV (sofosbuvir/ledipasvir), PrOD (ombitasvir/paritaprevir/ritonavir with dasabuvir) (Phase 1 only), EBR/GZR (elbasvir/grazoprevir) - Chronic Hepatitis C | Phase 4 | Completed | University of Florida | 1275 | 2016-06-01 | 2021-12-06 |
Hepatitis C (8) · Hepatitis C, Chronic (3) · Kidney Failure, Chronic (2) · Acquired Immunodeficiency Syndrome (1) · Cardiovascular Diseases (1) · Cross Infection (1) · Renal Insufficiency (1) · Renal Insufficiency, Chronic (1)
University of Maryland, Baltimore (3) · Johns Hopkins University (1) · Kyushu University (1) · Massachusetts General Hospital (1) · Raymond T. Chung, MD (1) · Taichung Veterans General Hospital (1) · Taoyuan General Hospital (1) · University of Florida (1) · University of Pennsylvania (1)
United States (7) · Taiwan (2) · Egypt (1) · Japan (1)
Chien-Yu Cheng (1) · David R Nelson, MD (1) · Jennifer S Husson, MD (1) · Michael R Rudnick, MD (1) · Norihiro Furusyo, MD, PhD (1) · Poonam Mathur, DO (1) · Raymond Chung, MD (1) · Raymond T Chung, MD (1) · Shyamasundaran Kottilil, MD, PhD (1) · Teng-Yu Lee, MD (1)
PMID 24073301, PMID 25909356, PMID 27720838, PMID 28193518, PMID 29507971, PMID 31114268, PMID 34255381, PMID 34902265, PMID 35182741, PMID 35657133