dual therapy: Clinical Trials

5 completed, 3 recruiting, 1 unknown, 1 withdrawn. 6 Phase 4, 2 Not applicable, 1 Phase 3.

By phase and status

Phase	Trials	Status
Phase 4	6	Recruiting 3, Completed 2, Withdrawn 1
Not applicable	2	Completed 1, Unknown 1
Phase 3	1	Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Efficacy, Safety, and ToLerability of Switching to A Two-Drug Regimen With DTG/3TC Compared to Maintaining A Three-Drug REgimen With BIC/FTC/TAF or DTG/3TC/ABC in ViroLogically SupprEssed PeopLe Living With HIV After 24 and 48 Weeks of Follow-Up Standard Medical Therapy, dual therapy - HIV Infections	Phase 4	Recruiting	José Antonio Mata Marín	156	2025-07-12	2025-08-22
Safety, Tolerability and Effectiveness of DTG/3TC vs BIC/TAF/FTC in PWH Without Antiretroviral Experience DTG/3TC, Bictegravir (BIC) plus Emtricitabine (FTC) plus Tenofovir Alafenamide (TAF) - HIV Infection, Metabolic Syndrome	Phase 4	Recruiting	Instituto Mexicano del Seguro Social	124	2025-04-01	2025-06-26
Effectiveness and Safety of Darunavir/Cobicistat Plus Lamivudine Versus Darunavir/Cobicistat Plus Tenofovir/Emtricitabine in Virologically Suppressed HIV-1-positive Individuals in Mexico dual therapy, Standard Medical Therapy - HIV Infection	Phase 4	Recruiting	José Antonio Mata Marín	138	2023-11-09	2025-04-04
A Phase IV Study to Assess the Impact of the Change of Antiretroviral Treatment From Dual Therapy to Triple Therapy on Inflammation in Patients With HIV Infection Dual Therapy, Triple therapy - HIV Infections	Phase 4	Completed	Fundacion SEIMC-GESIDA	141	2019-10-10	2024-10-01
Dolutegravir-Lamivudine as Dual Therapy in naïve HIV-Infected Patients With Documented M184V Mutation:A Pilot Study Dolutegravir plus lamivudine - HIV-1 Infection	Phase 4	Withdrawn	Pedro Cahn		2019-05-22	2022-04-12
Dual Obstructive Sleep Apnea Therapy Dual Therapy - Obstructive Sleep Apnea	Not applicable	Unknown	University of British Columbia	30	2018-03-08	2018-05-02
Metoclopramide-Ondansetron vs. Metoclopramide Therapy for Treatment of Nausea and Vomiting Post Laparoscopic Surgery Dual therapy, Monotherapy, General anesthesia - Postoperative Nausea and Vomiting	Not applicable	Completed	Makassed General Hospital	120	2018-02-15	2019-09-27
APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF Dual Therapy, Triple Therapy - Acute Coronary Syndrome, Atrial Fibrillation	Phase 4	Completed	LMU Klinikum	403	2016-06-01	2020-08-14
Trial to Evaluate the Interest of a Reductive Anti Retroviral Strategy Using Dual Therapy Inspite of Triple Therapy triple therapy, dual therapy - HIV	Phase 3	Completed	University Hospital, Tours	224	2014-12-01	2025-12-26
Duration of Dual Antiretroviral Therapy in Virologically Suppressed People Living With HIV and Factors Associated With Switching to Tritherapy : a Real-life Cohort dual therapy - HIV Infections		Completed	Tourcoing Hospital	580	2011-01-01	2023-11-01

Conditions studied

HIV Infections (5)  ·  Acute Coronary Syndrome (1)  ·  Atrial Fibrillation (1)  ·  Coronary Artery Disease (1)  ·  Metabolic Syndrome (1)  ·  Postoperative Nausea and Vomiting (1)  ·  Sleep Apnea, Obstructive (1)

Sponsors

José Antonio Mata Marín (2)  ·  Fundacion SEIMC-GESIDA (1)  ·  Instituto Mexicano del Seguro Social (1)  ·  LMU Klinikum (1)  ·  Makassed General Hospital (1)  ·  Pedro Cahn (1)  ·  Tourcoing Hospital (1)  ·  University Hospital, Tours (1)  ·  University of British Columbia (1)

Countries

Mexico (3)  ·  France (2)  ·  Argentina (1)  ·  Canada (1)  ·  Germany (1)  ·  Lebanon (1)  ·  Spain (1)

Top investigators

Reza Wakili, MD (1)

Results publications

PMID 31350995, PMID 39055703