52 completed, 45 recruiting, 31 unknown, 19 not yet recruiting. 180 Phase 1, 76 Phase 2.
Follow Drug Therapy: new trials by email Literature Review of Drug Therapy trials Research Report on Drug Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial Actigraphy, Best Practice, Biospecimen Collection - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Theodore Brasky PhD | 50 | 2027-01-15 | 2026-10-14 |
| BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia | Phase 1 | Not yet recruiting | City of Hope Medical Center | 19 | 2026-12-14 | 2026-05-13 |
| A Phase I Study of HS-20093 Injection in Combination Therapy in Non-Small Cell Lung Cancer HS-20093, Ivonescimab, Chemotherapy - Non-Small Cell Lung Cancer | Phase 1 | Not yet recruiting | Hansoh BioMedical R&D Company | 102 | 2026-11-10 | 2026-10-27 |
| Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 / Phase 2 | Recruiting | Ruijin Hospital | 78 | 2026-11-01 | 2026-10-26 |
| IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer FH-STEAP1 IL-18 CAR T cells, Antiandrogen Therapy, Biospecimen Collection - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 1 | Not yet recruiting | Fred Hutchinson Cancer Center | 20 | 2026-10-31 | 2026-09-04 |
| Safety and Efficacy of Ubamatamab With First-line Chemotherapy in Ovarian Cancer Ubamatamab, Chemotherapy, Bevacizumab - Ovarian Cancer | Phase 1 / Phase 2 | Not yet recruiting | ARCAGY/ GINECO GROUP | 43 | 2026-08-01 | 2026-07-10 |
| A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of LRK-4189 Alone and in Combination in Patients With Solid Tumors LRK-4189 escalation, LRK-4189 expansion, LRK-4189 optimization - Neoplasms | Phase 1 / Phase 2 | Recruiting | LARKSPUR BIOSCIENCES, INC. | 120 | 2026-07-07 | 2026-07-13 |
| Peptide Nanovaccine (ONVAX-01) Plus Anti-PD-1 Antibody and Chemotherapy in Advanced Pancreatic Cancer ONVAX-01 plus Anti-PD-1 and Chemotherapy - Advanced Pancreatic Adenocarcinoma | Phase 1 | Not yet recruiting | Sichuan University | 9 | 2026-06-20 | 2026-06-10 |
| Perioperative Zanidatamab and Chemotherapy for HER2 Positive Gastroesophageal Cancer Zanidatamab Combined with Chemotherapy - Gastroesophageal Cancer | Phase 1 / Phase 2 | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 29 | 2026-06-01 | 2026-03-20 |
| Propranolol Hydrochloride Combined With Toripalimab and Platinum-based Chemotherapy in Resectable Non-Small Cell Lung Cancer Propranolol Hydrochloride, Toripalimab, Chemotherapy - Resectable Non-Small-Cell Lung Cancer | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 9 | 2026-06-01 | 2026-10-21 |
| Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung Cancer Propranolol Hydrochloride, Adebrelimab, Chemotherapy - Small Cell Lung Cancer (SCLC) | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 18 | 2026-05-29 | 2026-10-21 |
| NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer NALIRIFOX+Adebrelimab, PULSAR - Pancreatic Ductal Adenocarcinoma (PDAC), Locally Advanced and Metastatic Pancreatic Cancer | Phase 1 / Phase 2 | Recruiting | West China Hospital | 55 | 2026-04-01 | 2026-05-19 |
| Lattice-Based Radiotherapy and Chemo-Immunotherapy for Oral Cavity Squamous Cell Carcinoma Chemotherapy, Lattice Radiotherapy (LRT) - Oral Cavity Squamous Cell Carcinoma | Phase 1 | Not yet recruiting | NYU Langone Health | 30 | 2026-04-01 | 2026-01-29 |
| Neoadjuvant Therapy With Ensartinib Combined With Chemotherapy for ALK-positive Non - Small Cell Lung Cancer (NSCLC) Ensartinib + Chemotherapy - NSCLC (Non-small Cell Lung Cancer) | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 20 | 2026-03-25 | 2026-04-01 |
| A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy of KRC-01 KRC-01, External Beam Radiation Therapy, cisplatin - Cervical Cancer | Phase 1 | Recruiting | Kortuc, Inc. | 70 | 2026-03-01 | 2026-04-08 |
| SYS6090 Combination Therapy in Advanced Lung Cancer SYS6090 + pemetrexed + platinum-based chemotherapy, SYS6090 + paclitaxel + platinum-based chemotherapy, SYS6090 + docetaxel - Non-Small Cell Lung Cancer, Small Cell Lung Cancer | Phase 1 / Phase 2 | Not yet recruiting | Shanghai JMT-Bio Inc. | 596 | 2026-02-28 | 2026-03-16 |
| Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer Biospecimen Collection, Chemotherapy, Decitabine - Human Papillomavirus-Negative Neck Squamous Cell Carcinoma, Resectable Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Mayo Clinic | 32 | 2026-01-23 | 2026-07-15 |
| Phase Ib/II Study to Evaluate the Safety and Efficacy of IBI363 in Combination With Chemotherapy as Second-Line Therapy for Unresectable Locally Advanced or Metastatic Pancreatic Cancer IBI363 + chemotherapy - Pancreatic Cancer Metastatic | Phase 1 / Phase 2 | Not yet recruiting | Ruijin Hospital | 48 | 2026-01-01 | 2026-01-15 |
| Phase 1 Study of Chemotherapy Plus HLA-mismatched GPBMC Infusion Bridging to Allo-HSCT for R/R Leukemia Chemotherapy, HLA-mismatched GPBMC infusion, Allogeneic Stem Cell Transplantation - Relapsed Leukemia, Refractory Leukemia | Phase 1 | Recruiting | Beijing 302 Hospital | 5 | 2025-12-01 | 2025-12-22 |
| Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer Entinostat, Chemotherapy - Bladder Cancer, Histone Deacetylase Inhibitor | Phase 1 / Phase 2 | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 29 | 2025-12-01 | 2025-12-03 |
Showing 20 of 180. Sign in to see all of them.
Carcinoma, Non-Small-Cell Lung (23) · Pancreatic Neoplasms (17) · Neoplasms (13) · Colorectal Neoplasms (11) · Neoplasm Metastasis (11) · Ovarian Neoplasms (11) · Breast Neoplasms (10) · Leukemia, Myeloid, Acute (9) · Stomach Neoplasms (9) · Glioblastoma (8) · Lung Neoplasms (8) · Squamous Cell Carcinoma of Head and Neck (8) · Mesothelioma, Malignant (7) · Carcinoma, Ovarian Epithelial (6) · Esophageal Neoplasms (6)
National Cancer Institute (NCI) (7) · Sichuan University (6) · Ruijin Hospital (5) · Memorial Sloan Kettering Cancer Center (4) · BeOne Medicines (3) · Second Xiangya Hospital of Central South University (3) · St. Jude Children's Research Hospital (3) · AbbVie (2) · Akeso (2) · BeiGene (2) · Chinese PLA General Hospital (2) · Clinical Oncology Research Associates (2) · Fred Hutchinson Cancer Center (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Hoffmann-La Roche (2)
United States (82) · China (67) · France (14) · United Kingdom (14) · Spain (11) · Australia (10) · Netherlands (8) · Germany (7) · South Korea (7) · Belgium (6) · Italy (5) · Canada (4) · Poland (4) · Japan (3) · New Zealand (3)
Huajun Jin (2) · Jiangtao Wang (2) · Paul Sabbatini, MD (2) · Paul Schwarzenberger, MD (2) · Qijun Qian (2) · You Lu, MD (2) · Adam L. Holtzman, MD (1) · Adam M Sonabend, MD (1) · Adam Ostrowski, MD (1) · Adrienne C Scheck, PhD (1)
PMID 39368878, PMID 15131031, PMID 16626792, PMID 17896890, PMID 20842054, PMID 21436454, PMID 21561347, PMID 22658128, PMID 24131140, PMID 24766732, PMID 25586952, PMID 25872567, PMID 25895027, PMID 25979230, PMID 27191266, PMID 29595064, PMID 31039052, PMID 31132111, PMID 31263030, PMID 33674274, PMID 33794306, PMID 33820822, PMID 34088831, PMID 34439389, PMID 34726575, PMID 34980038, PMID 35293148, PMID 35534566, PMID 35552677, PMID 37046691, PMID 37084803, PMID 37142373, PMID 37280366, PMID 37459862, PMID 37689733, PMID 37708904, PMID 37820884, PMID 38148327, PMID 38572751, PMID 38589494, PMID 38788174, PMID 38830992, PMID 38834087, PMID 39008192, PMID 39089313, PMID 39448025, PMID 39473059, PMID 39687891, PMID 39724015, PMID 40062648
2023 (3), 2016 (2), 2017 (2), 2014 (1), 2018 (1), 2025 (1), P30CA033572 (1), P30CA068485 (1), P50CA097257 (1), R01CA109767 (1), R01CA113482 (1), R01CA195473 (1), R01CA273028 (1), R03MH060940 (1), R37CA287204 (1)