10 completed, 1 active not recruiting. 11 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 10, Active not recruiting 1 |
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
Follow Deferiprone: new trials by email Literature Review of Deferiprone trials Research Report on Deferiprone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ferritin and Iron Burden in SAH sIRB Deferiprone pill, placebo, Montreal Cognitive Assessment - SAH, Dementia | Phase 1 / Phase 2 | Active not recruiting | Duke University | 66 | 2020-10-01 | 2026-07-20 |
| Characterisation of Relative Bioavailability With Bioequivalence Assessment of Deferiprone Tablets After Oral Single Dose Administration Deferiprone 500Mg Tablet, Deferiprone 500 MG Oral Tablet [Ferriprox] - Bioequivalence | Phase 1 | Completed | SocraTec R&D GmbH | 25 | 2016-08-01 | 2016-12-07 |
| Comparison of Deferiprone Extended Release Tablets and Ferriprox Immediate Release Tablets in Healthy Volunteers Deferiprone extended release, Deferiprone immediate release - Healthy | Phase 1 | Completed | ApoPharma | 20 | 2015-06-01 | 2016-02-26 |
| Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects Intravenous deferiprone, Placebo - Asymptomatic HIV Infection | Phase 1 | Completed | ApoPharma | 30 | 2015-06-01 | 2016-06-07 |
| Comparison of Deferiprone Delayed Release Tablets and Deferiprone Oral Solution in Healthy Volunteers Deferiprone delayed release tablet formulation, Deferiprone oral solution - Healthy | Phase 1 | Completed | ApoPharma | 20 | 2015-05-01 | 2016-05-13 |
| Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy Volunteers Deferiprone sustained-release, Deferiprone immediate-release - Healthy | Phase 1 | Completed | ApoPharma | 11 | 2014-05-01 | 2016-05-20 |
| A Blinded, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single Doses of Intravenous Deferiprone in Healthy Volunteers Deferiprone, Placebo - Healthy Volunteers | Phase 1 | Completed | ApoPharma | 64 | 2013-11-01 | 2014-12-23 |
| Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease single 1500 mg dose of Ferriprox - Sickle Cell Disease | Phase 1 | Completed | ApoPharma | 8 | 2013-05-01 | 2015-07-24 |
| Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia Deferasirox and deferiprone - Thalassemia Major With Severe Transfusional Iron Overload | Phase 1 / Phase 2 | Completed | Children's Hospital of Philadelphia | 9 | 2012-09-01 | 2019-03-06 |
| A Study Investigating the Safety and Tolerability of Deferiprone in Patients With Friedreich's Ataxia placebo, deferiprone - Friedreich's Ataxia | Phase 1 / Phase 2 | Completed | ApoPharma | 80 | 2008-04-01 | 2010-06-02 |
| Antiretroviral Activity and Pharmacokinetics of Deferiprone in Healthy Volunteers and Asymptomatic HIV-infected Subjects Deferiprone - HIV Infection | Phase 1 | Completed | ApoPharma | 26 | 2006-11-01 | 2014-07-16 |
HIV Infections (2) · Anemia, Sickle Cell (1) · Dementia (1) · Friedreich Ataxia (1) · Iron Overload (1) · Thalassemia (1)
ApoPharma (8) · Children's Hospital of Philadelphia (1) · Duke University (1) · SocraTec R&D GmbH (1)
Canada (6) · South Africa (2) · United States (2) · Australia (1) · Belgium (1) · France (1) · Germany (1) · Italy (1) · Spain (1)
Fernando Tricta, MD (2) · Arnold Munnich, M.D. (1) · Cornelius Koch, MD (1) · David Hasan, MD (1) · Denis Soulieres, MD (1) · Dewald Steyn, MD (1) · Eric Sicard, MD (1) · Franco Taroni (1) · Gurinder Rai, MD (1) · Janet L Kwiatkowski, MD, MSCE (1) · Javier Arpa (1) · Mark Tarnopolsky, MD (1) · Martin Delatycki (1) · Massimo Pandolfo, M.D. (1)