4 completed, 3 active not recruiting, 3 recruiting, 2 unknown. 5 Phase 2, 4 Not applicable, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 3, Completed 1, Recruiting 1 |
| Not applicable | 4 | Recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Craniospinal Irradiation: new trials by email Literature Review of Craniospinal Irradiation trials Research Report on Craniospinal Irradiation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer Biospecimen Collection, Craniospinal Irradiation, Electronic Health Record Review - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 35 | 2025-05-05 | 2025-12-08 |
| Craniospinal Irradiation in Histone AlteRed Midline Glioma craniospinal irradiation - Glioma | Not applicable | Recruiting | Tata Memorial Centre | 32 | 2025-01-03 | 2025-01-20 |
| Infracalcaneal Peppering Injection Technique for Chronic Plantar Fasciitis Corticosteroid injection (CSI) with local anesthetic (LA), Local anesthetic (LA) with Saline injection - Chronic Plantar Fasciitis | Phase 1 | Completed | Wake Forest University Health Sciences | 41 | 2023-10-18 | 2025-10-30 |
| Feasibility of Home Exercises With the Addition of a Corticosteroid Injection in Patients With Lateral Hip Pain in General Practice Exercises and CSI - Lateral Hip Pain, Gluteal Tendinopathy | Not applicable | Unknown | Aalborg University | 20 | 2021-10-01 | 2021-10-21 |
| Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma. Low dose Craniospinal Irradiation plus Focal Radiotherapy - Medulloblastoma, WNT-activated | Not applicable | Recruiting | Tata Memorial Centre | 30 | 2020-08-13 | 2025-04-09 |
| Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors alisertib, methotrexate, cisplatin - Malignant Rhabdoid Tumor, Atypical Teratoid Rhabdoid Tumor | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 125 | 2014-05-14 | 2026-09-01 |
| A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma Irradiation, Surgery, ^1^8F-Fluorodeoxyglucose - Ependymoma | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 68 | 2014-05-07 | 2026-02-24 |
| A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma Craniospinal Irradiation with boost to the primary tumor site, Cyclophosphamide, Cisplatin - Medulloblastoma | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 660 | 2013-06-23 | 2025-11-13 |
| Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors craniospinal irradiation, Carboplatin, Etoposide, Ifosfamide, ventricular irradiation - Intracranial Germ Cell Tumors | Phase 4 | Unknown | University Hospital Muenster | 400 | 2011-10-01 | 2015-06-04 |
| Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Cisplatin, Craniospinal Irradiation, Cyclophosphamide - Medulloblastoma | Phase 3 | Completed | Children's Oncology Group | 549 | 2004-04-30 | 2026-06-09 |
| Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors carboplatin, etoposide, ifosfamide - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | Children's Oncology Group | 104 | 2004-01-01 | 2018-02-14 |
| Tidal Irrigation Versus Intra-articular Steroid Injection in the Treatment of Knee Osteoarthritis Intra-articular CSI, TI of the knee - Knee Osteoarthritis | Not applicable | Completed | Portsmouth Hospitals NHS Trust | 150 | 2000-11-01 | 2017-04-24 |
Medulloblastoma (3) · Brain Neoplasms (2) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Central Nervous System Neoplasms (1) · Ependymoma (1) · Fasciitis, Plantar (1) · Glioma (1) · Infratentorial Neoplasms (1) · Lung Neoplasms (1) · Meningeal Carcinomatosis (1) · Neuroectodermal Tumors, Primitive (1) · Osteoarthritis, Knee (1) · Rhabdoid Tumor (1) · Teratoma (1)
St. Jude Children's Research Hospital (3) · Children's Oncology Group (2) · Tata Memorial Centre (2) · Aalborg University (1) · City of Hope Medical Center (1) · Portsmouth Hospitals NHS Trust (1) · University Hospital Muenster (1) · Wake Forest University Health Sciences (1)
United States (7) · Australia (3) · Canada (3) · New Zealand (3) · India (2) · Switzerland (2) · Denmark (1) · Germany (1) · Netherlands (1) · Puerto Rico (1)
Amar Gajjar, MD (2) · Abhishek Chatterjee, MD (1) · Gabriele Calaminus, MD (1) · Giles Robinson, MD (1) · Jeff M Michalski (1) · Michael A Jones, DPM (1) · Nigel K Arden (1) · Stephanie M Yoon (1) · Stewart Goldman, MD (1) · Thomas E. Merchant, DO, PhD (1)
PMID 31545689, PMID 33633029, PMID 33823018, PMID 34110925, PMID 40073837
2009 (1), P30CA033572 (1), R01CA187079 (1), U10CA098543 (1), U10CA180886 (1), UL1TR001420 (1)