26 completed. 26 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 26 | Completed 26 |
| Phase 2 | 3 | Completed 3 |
Follow Corticosteroids: new trials by email Literature Review of Corticosteroids trials Research Report on Corticosteroids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura Caplacizumab, Corticosteroids, anti-CD20 antibody - Thrombotic Thrombocytopenic Purpura | Phase 3 | Completed | Sanofi | 51 | 2022-11-21 | 2025-12-30 |
| Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus Lycopene Softgel, 10 Mg, Prednisolone - Erosive Lichen Planus | Phase 2 / Phase 3 | Completed | Nourhan M.Aly | 20 | 2018-10-01 | 2020-12-03 |
| Combination Corticosteroids+5-aminosalicylic Acids Compared to Corticosteroids Alone (for Ulcerative Colitis). 5-ASA, Corticosteroids - Ulcerative Colitis | Phase 3 | Completed | Centre Hospitalier Universitaire de Saint Etienne | 160 | 2016-06-13 | 2021-08-26 |
| An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA) Tocilizumab, Prednisone, Tocilizumab Placebo - Giant Cell Arteritis | Phase 3 | Completed | Hoffmann-La Roche | 251 | 2013-07-22 | 2020-02-06 |
| 12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients Everolimus, Tacrolimus, Cyclosporin A - Kidney Transplantation, Renal Transplantation | Phase 3 | Completed | Novartis Pharmaceuticals | 612 | 2012-12-27 | 2017-05-01 |
| A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients tacrolimus, everolimus, Basiliximab - Liver Transplantation | Phase 3 | Completed | Novartis Pharmaceuticals | 188 | 2012-12-01 | 2016-04-27 |
| Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium Tacrolimus, Everolimus, Enteric Coated Mycophenolate Sodium (EC-MPS) - Transplant; Failure, Kidney | Phase 3 | Completed | Gaetano Ciancio | 32 | 2012-11-01 | 2016-12-15 |
| Optic Neuritis Recovery After Oral or IV Corticosteroids corticosteroids - Optic Neuritis | Phase 2 / Phase 3 | Completed | London Health Sciences Centre | 51 | 2012-03-01 | 2015-09-02 |
| A Study of LY2127399 in Participants With Systemic Lupus Erythematosus LY2127399, Placebo every 2 weeks, Placebo every 4 weeks - Systemic Lupus Erythematosus, Connective Tissue Disease | Phase 3 | Completed | Eli Lilly and Company | 1164 | 2010-12-01 | 2018-06-12 |
| The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy. Oral Prednisone, Placebo comparator - Nasal Polyps | Phase 3 | Completed | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | 34 | 2010-11-01 | 2014-01-10 |
| Ciclosporin in the Management of New Type 1 Reactions in Leprosy Ciclosporin, Prednisolone - Leprosy | Phase 2 / Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 73 | 2010-08-01 | 2015-03-24 |
| Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients Tacrolimus (reduced tacrolimus), Everolimus (reduced tacrolimus), Tacrolimus (tacrolimus elimination) - Liver Transplant Recipient | Phase 3 | Completed | Novartis Pharmaceuticals | 284 | 2010-03-31 | 2018-11-07 |
| Phase 3b Study to Evaluate Advagraf in Combination With Mycophenolate Mofetil and Basiliximab in Liver Transplantation Advagraf, Mycophenolate Mofetil, Basiliximab - Liver Transplantation | Phase 3 | Completed | Astellas Pharma Inc | 893 | 2009-09-30 | 2024-11-01 |
| Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients Certican®, Neoral, Myfortic - Renal Interstitial Fibrosis | Phase 3 | Completed | Novartis Pharmaceuticals | 194 | 2009-09-01 | 2014-03-18 |
| Comparison of Standard Versus Low Dose Advagraf® With or Without Angiotensin-converting Enzyme Inhibitor (ACEi)/Angiotensin Receptor Blocker (ARB) on Histology and Function of Renal Allografts tacrolimus, Simulect, Cellcept - Kidney Transplantation | Phase 3 | Completed | Astellas Pharma Inc | 281 | 2009-08-17 | 2024-11-01 |
| A Study of Prophylactic Treatment for Hand-Foot Syndrome in Patients Treated With Oral Xeloda (Capecitabine). Corticosteroids, Placebo, capecitabine [Xeloda] - Breast Cancer | Phase 3 | Completed | Hoffmann-La Roche | 598 | 2008-12-01 | 2016-11-02 |
| A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA) tocilizumab [RoActemra/Actemra], Placebo, Non-steroidal anti-inflammatory drugs (NSAIDs) - Juvenile Idiopathic Arthritis | Phase 3 | Completed | Hoffmann-La Roche | 112 | 2008-05-01 | 2016-07-25 |
| Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes Phenytoin (brand name Dilantin), Hydrocortisone, Placebo - Healthy | Phase 3 | Completed | University of Texas Southwestern Medical Center | 17 | 2008-01-01 | 2015-08-19 |
| Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients Tacrolimus (reduced tacrolimus), Tacrolimus (tacrolimus elimination), Tacrolimus (tacrolimus control) - Liver Transplantation | Phase 3 | Completed | Novartis Pharmaceuticals | 719 | 2008-01-01 | 2013-05-27 |
| A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Heart Transplant Patients. mycophenolate mofetil (MMF), cyclosporine A (CsA), corticosteroids - Heart Transplantation | Phase 3 | Completed | Hoffmann-La Roche | 36 | 2006-08-01 | 2014-10-29 |
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Graft vs Host Disease (2) · Arthritis, Juvenile (1) · Asthma (1) · Autoimmune Diseases (1) · Blood Loss, Surgical (1) · Breast Neoplasms (1) · Colitis, Ulcerative (1) · Connective Tissue Diseases (1) · Demyelinating Diseases (1) · Dyspnea (1) · Giant Cell Arteritis (1) · Heart Diseases (1) · Immune System Diseases (1) · Kidney Diseases (1) · Leprosy (1)
Novartis Pharmaceuticals (6) · Hoffmann-La Roche (5) · Astellas Pharma Inc (2) · Novartis (2) · Centre Hospitalier Universitaire de Saint Etienne (1) · Eli Lilly and Company (1) · Gaetano Ciancio (1) · Genentech, Inc. (1) · London Health Sciences Centre (1) · London School of Hygiene and Tropical Medicine (1) · Nourhan M.Aly (1) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (1) · Sanofi (1) · University of Texas Southwestern Medical Center (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
Canada (11) · France (11) · United States (11) · Germany (10) · Italy (9) · Belgium (8) · Spain (8) · United Kingdom (8) · Sweden (7) · Argentina (6) · Australia (5) · Brazil (5) · Czechia (5) · Netherlands (5) · Norway (5)
Aliaa A Bedeir, BDS (1) · Azza M Zaki, PhD (1) · Diana Lockwood, MBChB (1) · Gaetano Ciancio, M.D. (1) · Ian Witterick, MD FRCSC (1) · Karin Rosen, M.D., Ph.D. (1)
PMID 21536936, PMID 22257543, PMID 23230975, PMID 23252525, PMID 23422495, PMID 23471469, PMID 23714399, PMID 25504861, PMID 26151607, PMID 26338095, PMID 26888217, PMID 27220348, PMID 27723281, PMID 28745999, PMID 28817434, PMID 29045736, PMID 29507942, PMID 30582281, PMID 30786937, PMID 30824645, PMID 30835950, PMID 31530561, PMID 31760132, PMID 31790472, PMID 32912276, PMID 33217063, PMID 33223095, PMID 33465457, PMID 34049857, PMID 34303017, PMID 34718434, PMID 35947992, PMID 38279390, PMID 38676311, PMID 38993854, PMID 39082471, PMID 39382091, PMID 39739990, PMID 41348038
2009 (2), 2008 (1), 2015 (1)