7 completed, 4 terminated, 1 unknown. 5 Phase 4, 3 Phase 2, 3 Phase 3, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 3 | Terminated 2, Completed 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Compazine: new trials by email Literature Review of Compazine trials Research Report on Compazine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness Prochlorperazine Maleate, Placebo - Acute Mountain Sickness | Phase 2 | Completed | University of Colorado, Denver | 57 | 2024-08-05 | 2024-09-19 |
| Intranasal Ketorolac Trial Ketorolac, Prochlorperazine, Diphenhydramine - Headache, Migraine | Phase 2 | Terminated | Washington University School of Medicine | 41 | 2024-01-01 | 2026-01-16 |
| Intravenous Fluids in Pediatric Migraine 1/2 maintenance fluids, Ketorolac, Diphenhydramine - Migraine, Migraine in Children | Not applicable | Unknown | Dayton Children's Hospital | 134 | 2023-06-27 | 2023-12-26 |
| Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients Ondansetron, Dexamethasone, Neurokinin-1 Receptor Antagonist (NK1-RA) - Gynecologic Cancer | Phase 3 | Terminated | University of Michigan Rogel Cancer Center | 62 | 2020-12-28 | 2025-06-18 |
| Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia - Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy | Phase 4 | Completed | Stony Brook University | 83 | 2017-08-28 | 2024-02-14 |
| Intravenous Fluids in Benign Headaches Trial Normal Saline 5mL, Normal Saline 20mL/kg, Prochlorperazine 0.15 mg/kg up to 10 mg IV - Headache | Phase 4 | Completed | University Medical Center of Southern Nevada | 58 | 2017-05-16 | 2024-06-06 |
| E7 TCR T Cells for Human Papillomavirus-Associated Cancers E7 TCR cells, Aldesleukin, Fludarabine - Papillomavirus Infections, Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 224 | 2017-01-27 | 2026-03-09 |
| The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine Compazine, Ketamine - Headache | Phase 3 | Terminated | Mike O'Callaghan Military Hospital | 5 | 2016-08-01 | 2024-03-04 |
| The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine Prochlorperazine, Ketamine, Diphenhydramine - Headache | Phase 4 | Completed | University Medical Center of Southern Nevada | 54 | 2016-03-17 | 2017-12-11 |
| Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine Hydromorphone, Prochlorperazine, Diphenhydramine - Migraine | Phase 4 | Completed | Montefiore Medical Center | 127 | 2015-03-01 | 2018-08-31 |
| Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine Aspirin, Acetaminophen, Caffeine pills, Prochlorperazine 10mg - Migraine Headaches | Phase 4 | Terminated | Albert Einstein Healthcare Network | 93 | 2010-11-01 | 2020-03-18 |
| Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial aprepitant, dexamethasone, granisetron hydrochloride - Nausea | Phase 3 | Completed | Joseph Roscoe | 1021 | 2006-12-01 | 2015-11-10 |
Headache (5) · Migraine Disorders (5) · Vomiting (2) · Altitude Sickness (1) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma in Situ (1) · Inflammatory Breast Neoplasms (1) · Nausea (1) · Papillomavirus Infections (1) · Uterine Cervical Dysplasia (1) · Vulvar Diseases (1) · Vulvar Neoplasms (1)
University Medical Center of Southern Nevada (2) · Albert Einstein Healthcare Network (1) · Dayton Children's Hospital (1) · Joseph Roscoe (1) · Mike O'Callaghan Military Hospital (1) · Montefiore Medical Center (1) · National Cancer Institute (NCI) (1) · Stony Brook University (1) · University of Colorado, Denver (1) · University of Michigan Rogel Cancer Center (1) · Washington University School of Medicine (1)
United States (12)
Aimee Rolston (1) · Benjamin W Friedman, MD, MS (1) · Christopher Pitotti, MD (1) · Elan Small, MD (1) · Jonathan Elliott, MD (1) · Joseph A Zitek, MD (1) · Joseph A. Roscoe, PhD (1) · Kenneth Deitch, DO (1) · Konstantinos Spaniolas, MD (1) · Scott M Norberg, D.O. (1) · Sophia Rifkin, MD (1) · Tony Zitek, MD (1)
PMID 11535479, PMID 12598264, PMID 12764341, PMID 14633551, PMID 15107371, PMID 17157685, PMID 18006188, PMID 18387702, PMID 18534808, PMID 18958996, PMID 20045576, PMID 21880111, PMID 22915657, PMID 23567060, PMID 23936605, PMID 24127709, PMID 24180163, PMID 25366551, PMID 25817884, PMID 29033296, PMID 29046364, PMID 29089172, PMID 2915441, PMID 32620543, PMID 33528788, PMID 33558725, PMID 34363617, PMID 39574186, PMID 7486359, PMID 9707750
U10CA037420 (1)