8 completed, 2 terminated, 2 unknown, 1 active not recruiting. 5 Phase 4, 4 Phase 3, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 3, Active not recruiting 1, Unknown 1 |
| Phase 3 | 4 | Completed 2, Not yet recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Not yet recruiting 1, Unknown 1 |
Follow colistimethate sodium: new trials by email Literature Review of colistimethate sodium trials Research Report on colistimethate sodium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| Comparative Study of Clinical Outcomes and Safety Between Colistin and Tigecycline Colistimethate Sodium, Tigecycline - Infection in ICU | Phase 4 | Active not recruiting | Beni-Suef University | 132 | 2024-12-01 | 2025-03-25 |
| Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I) CMS, Placebo - Non Cystic Fibrosis Bronchiectasis | Phase 3 | Completed | Zambon SpA | 377 | 2017-06-06 | 2023-11-15 |
| Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative Infections Colistimethate Sodium - Gram-Negative Bacterial Infections, Pediatric Cancer | Phase 4 | Completed | National Cancer Institute, Egypt | 70 | 2017-01-01 | 2020-09-16 |
| A Study of DEcolonization in Patients With HAematological Malignancies (DEHAM) Colistimethate Sodium - Hematological Infection | Phase 4 | Completed | Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology | 62 | 2017-01-01 | 2017-12-28 |
| Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in Neonates Aerosolized plus intravenous colistin, Intravenous colistin - Pneumonia, Ventilator-Associated, Colistin Adverse Reaction | Phase 3 | Terminated | Hat Yai Medical Education Center | 204 | 2016-09-01 | 2018-08-02 |
| Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection colistimethate sodium - Acinetobacter Infections | Completed | DongGuk University | 30 | 2015-05-01 | 2018-06-26 | |
| A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) plazomicin, colistin, meropenem - Bloodstream Infections (BSI) Due to CRE, Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Phase 3 | Completed | Achaogen, Inc. | 69 | 2014-09-16 | 2018-10-16 |
| Efficacy and Mortality of a Loading Dose of Colistin in Critical Ill Patients colistin - Gram Negative Bacterial Infections | Phase 4 | Unknown | Hospital Barros Luco Trudeau | 200 | 2014-04-01 | 2018-03-13 |
| Efficacy and Safety of Colistimethate Sodium Injection Vial to Treat Hospital-acquired Pneumonia in Adults Colistimethate sodium - Hospital-acquired Pneumonia | Phase 2 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 60 | 2013-10-01 | 2013-09-12 |
| Evaluation of Pharmacokinetic and Pharmacodynamic Properties of Intravenous Colistimethate Sodium colistimethate sodium - Colistin | Completed | University of Colorado, Denver | 16 | 2013-09-01 | 2019-06-24 | |
| Aerosolized and Intravenous Colistin in Healthy Adults Colistimethate sodium - Pathogen Resistance, Pneumococcal Infection | Phase 1 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 27 | 2013-08-06 | 2020-03-02 |
| Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus Meropenem Colistin, Meropenem - Gram-Negative Bacterial Infections | Phase 4 | Completed | Mical Paul | 406 | 2013-03-01 | 2017-04-12 |
| Phase I Study of Colistin Methanesulfonate Sodium Colistimethate sodium, Saline - Infections, Pseudomonas | Phase 1 | Completed | GlaxoSmithKline | 22 | 2010-10-23 | 2017-07-21 |
Gram-Negative Bacterial Infections (3) · Pneumonia (3) · Healthcare-Associated Pneumonia (2) · Pneumonia, Ventilator-Associated (2) · Acinetobacter Infections (1) · Bacterial Infections (1) · Critical Illness (1) · Cystic Fibrosis (1) · Neoplasms (1) · Pneumococcal Infections (1) · Pseudomonas Infections (1) · Renal Insufficiency (1) · Sepsis (1)
Achaogen, Inc. (1) · Beni-Suef University (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · DongGuk University (1) · GlaxoSmithKline (1) · Hat Yai Medical Education Center (1) · Hospital Barros Luco Trudeau (1) · Mical Paul (1) · Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology (1) · National Cancer Institute, Egypt (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · University Hospital Fattouma Bourguiba (1) · University of Colorado, Denver (1) · Zambon SpA (1)
Australia (2) · Egypt (2) · Greece (2) · Israel (2) · Italy (2) · United States (2) · Belarus (1) · Belgium (1) · Chile (1) · China (1) · Germany (1) · Netherlands (1) · New Zealand (1) · Portugal (1) · South Korea (1)
Ihar Iskrou, Ph.D. (1) · Johan Mouton, MD PhD (1) · Loreto Rojas, MD, PhD (1) · Lynn E Connolly, MD, PhD (1) · Mical Paul, MD (1) · Narongsak Nakwan, MD (1) · Ty Kiser, PharmD (1) · Yosr Samia Abou Sedira (1) · Young-Soon Yoon, professor (1)
PMID 21995648, PMID 27098822, PMID 29456043, PMID 29755707, PMID 30462182, PMID 31254273, PMID 33789574, PMID 34775134, PMID 41194117
2015 (1)