40 completed, 11 unknown, 2 not yet recruiting, 2 recruiting. 51 Not applicable, 2 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 51 | Completed 33, Unknown 11, Not yet recruiting 2, Recruiting 2, Terminated 2, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Coffee Consumption Immediately Before a Nap on Post-Nap Grumpiness Coffee, Placebo - Irritability | Not applicable | Not yet recruiting | Hightower Clinical | 50 | 2026-07-01 | 2026-06-09 |
| Effects of Coffee Versus Hibiscus Tea Consumption During Prolonged Sitting on Blood Pressure and Heart Rate Coffee, Hibiscus drink - Hypertension | Not applicable | Not yet recruiting | King Saud University | 30 | 2025-09-01 | 2025-09-08 |
| Association of Coffee Consumption With Peri-Implant Status Coffee - Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis | Completed | Tuğba ŞAHİN | 291 | 2024-12-07 | 2026-08-05 | |
| Association of Coffee With Periodontal Status coffee - Periodontal Diseases | Completed | Tuğba ŞAHİN | 318 | 2024-11-19 | 2026-08-03 | |
| Effect of Coffee and Agave Inulin-based Beverage on Appetite in Adults With Obesity. Coffee and agave inulin-based beverage (A), Control beverage (B) - Obesity | Not applicable | Unknown | University of Guadalajara | 30 | 2024-06-24 | 2024-07-30 |
| Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families CAFES2 - Depression, Anxiety | Not applicable | Recruiting | University of Illinois at Chicago | 74 | 2024-05-31 | 2025-10-01 |
| Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity Coffee capsule, Corn starch capsule - Prediabetes | Not applicable | Unknown | Nanjing First Hospital, Nanjing Medical University | 100 | 2024-02-05 | 2024-03-26 |
| The Acute Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes Coffee - Type 2 Diabetes | Not applicable | Completed | University of Reading | 40 | 2023-11-09 | 2026-02-19 |
| Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics Coffee, Water - Individual Variability in (Poly)Phenol Metabolism | Not applicable | Recruiting | University of Parma | 30 | 2023-10-25 | 2025-04-08 |
| The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters Warm water at 35 oC, Coffee, Honey-sweetened coffee - Blood Pressure, Heart Rate | Not applicable | Completed | University of Uyo Teaching Hospital | 70 | 2023-10-17 | 2025-06-15 |
| Effect of Flavored on!® Nicotine Pouch Products on Smoking Behaviors: a SMART Study Access to all varieties of on! 4mg nicotine pouches (Berry, Citrus, Cinnamon, Wintergreen, Mint, Coffee, and Original), Access to Original on! 4mg nicotine pouches, Non-Flavored then complete flavor on! nicotine pouches - Cigarette Smoking Behavior | Not applicable | Unknown | Altria Client Services LLC | 400 | 2023-09-11 | 2024-07-11 |
| ArtemiCoffee in Patients With Rising PSA ArtemiCoffee - Prostate Cancer | Phase 2 | Completed | Zin W Myint | 20 | 2023-08-11 | 2026-08-11 |
| The Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes Coffee - Type 2 Diabetes | Not applicable | Unknown | University of Reading | 70 | 2023-01-01 | 2023-02-02 |
| Effects of Espresso on Platelet Aggregability in Patients with Coronary Artery Disease Coffee - Coronary Artery Disease | Not applicable | Completed | University of Sao Paulo | 29 | 2022-09-01 | 2025-02-13 |
| Effects of Enhancers and Inhibitors on Absorption From Iron Supplements Reference, Ascorbic acid (AA) 500 mg, Ascorbic acid (AA) 80 mg - Iron-deficiency, Iron Deficiency Anemia | Not applicable | Completed | Swiss Federal Institute of Technology | 35 | 2022-06-20 | 2024-01-25 |
| Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia coffee, Water - Hypotension After Spinal Anesthesia, Post-Dural Puncture Headache | Completed | TC Erciyes University | 2 | 2022-03-15 | 2024-05-16 | |
| The Effect of Coffee and Hot Water on Gastroıntestınal Functıons Coffee, Hot water - COFFEE, Gastrointestinal Motility and Defecation Conditions | Not applicable | Completed | Mersin University | 77 | 2022-02-01 | 2023-08-08 |
| Effect of Coffee Consumption on Appetite Traits in Overweight and Obesity breakfast with coffee, breakfast with water - Obesity | Not applicable | Completed | University of Guadalajara | 10 | 2022-01-31 | 2024-02-14 |
| Impact of Coffee vs Orange Juice on Enhancing Recovery After Laparoscopic Colorectal Surgery Coffee, Orange juice - Colorectal Surgery | Not applicable | Unknown | National Cancer Institute, Egypt | 80 | 2021-11-22 | 2021-12-22 |
| Can Coffee/Caffeine Improve Post-Operative Gastrointestinal Recovery Coffee, Decaffeinated Coffee, Warm water - Postoperative Ileus, Caffeine | Not applicable | Completed | Sunnybrook Health Sciences Centre | 174 | 2021-10-05 | 2026-01-12 |
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Obesity (7) · Diabetes Mellitus, Type 2 (3) · Insulin Resistance (3) · Anxiety Disorders (2) · Headache (2) · Hypertension (2) · Inflammation (2) · Overweight (2) · Anemia, Iron-Deficiency (1) · Appetitive Behavior (1) · Arthralgia (1) · Arthritis (1) · Asymptomatic Diseases (1) · Body Weight (1) · Burnout, Professional (1)
Société des Produits Nestlé (SPN) (3) · Tuğba ŞAHİN (2) · University Hospital Heidelberg (2) · University of Guadalajara (2) · University of Reading (2) · Altria Client Services LLC (1) · Armed Forces Hospitals, Southern Region, Saudi Arabia (1) · Azienda Ospedaliera di Padova (1) · Brasilia University Hospital (1) · Cairo University (1) · Chiang Mai University (1) · Clinical Nutrition Research Center, Illinois Institute of Technology (1) · Erzincan Military Hospital (1) · G. d'Annunzio University (1) · Harokopio University (1)
United States (18) · Turkey (Türkiye) (6) · Switzerland (4) · Brazil (3) · Canada (2) · Germany (2) · Italy (2) · Mexico (2) · Saudi Arabia (2) · China (1) · Denmark (1) · Egypt (1) · Greece (1) · Israel (1) · Lebanon (1)
Maurice Beaumont, MD (2) · Ahmed M Mahmoud, Professor (1) · Brandon Ballhaus, BSN, RN (1) · Britt Burton-Freeman, Ph.D (1) · Brody Holohan, PhD (1) · Caio EG Reis, MSc (1) · Christoph Eisenbach (1) · Christopher Thompson, PT, PhD (1) · Damrong Wiwatwongwana, M.D. (1) · Daniel Lamport, PhD (1) · David S Goldstein, M.D. (1) · Dominik P Guensch, MD (1) · Dorota Krajewski, MD (1) · Esther O Aluko (1) · Fernando Aguila, MD (1)
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