11 completed, 1 recruiting. 7 Not applicable, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Cigarette Smoking: new trials by email Literature Review of Cigarette Smoking trials Research Report on Cigarette Smoking
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Effect of Nicotine on Eye Movements and Related Behaviors in Electronic Cigarette Users, NICS-EYES Trial Avoidance, Biospecimen Collection, Cigarette Smoking - Cigarette Smoking-Related Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 25 | 2026-08-17 | 2026-10-05 |
| Randomized Controlled Trial to Evaluate the Impact of ZYN Nicotine Pouch Products on Cigarette Usage and BoExp in Adult Smokers Over a 12-week Period cigarette smoking, tobacco flavored and unflavored pouch, unrestricted flavor options pouch - Tobacco Use | Not applicable | Completed | Swedish Match AB | 450 | 2023-07-31 | 2024-08-23 |
| Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking THS use, Cigarette smoking, Smoking abstinence - Inflammation, Oxidative Stress | Completed | Philip Morris Products S.A. | 974 | 2022-06-13 | 2026-05-08 | |
| Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study Cigarette Smoking, Computed Tomography, Positron Emission Tomography - Cigarette Smoking-Related Carcinoma | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 21 | 2022-03-23 | 2025-03-24 |
| Appeal of Nicotine Pouches Versus Cigarettes in the Ohio Appalachia Population Cigarette Smoking, Nicotine Oral Pouch, Questionnaire Administration - Cigarette Smoking-Related Carcinoma | Early Phase 1 | Completed | Ohio State University Comprehensive Cancer Center | 55 | 2022-03-01 | 2024-05-21 |
| The Effect of Aerosol Formed From Tobacco Heating Systems on the Microbiome of Supragingival Dental Biofilm Tobacco heating systems, cigarette smoking, non smoking - Dental Caries | Completed | University of Rijeka | 60 | 2021-10-01 | 2024-03-15 | |
| Effect of Smoking on Retinal Vessel Morphology and Functionality Cigarette Smoking - Smokers | Not applicable | Completed | IRCCS San Raffaele | 40 | 2021-04-01 | 2025-12-03 |
| Acute Health Effects of Short-term Use of E-cigarettes on Pulmonary and Cardiovascular System Cigarette smoking, E-cigarette use, Simulation of the use of e-cigarette - E-cigarette | Not applicable | Completed | Medical University of Silesia | 120 | 2017-01-01 | 2018-11-15 |
| Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels caffeine intake, cigarette smoking, Caffeine intake and Cigarette smoking - Hemodynamic Instability, Skin and Subcutaneous Tissue Disorders | Not applicable | Completed | Technological Education Institute of Sterea Ellada | 178 | 2012-11-01 | 2015-09-09 |
| The Effect of Smoking on Thermoregulation Nicotine, cigarette smoking - Cigarette Smoking | Not applicable | Completed | Sheba Medical Center | 16 | 2012-06-01 | 2014-05-09 |
| The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking Bendavia, Sterile saline (0.9%), Cigarette smoking - Healthy Volunteers | Phase 1 | Completed | Stealth BioTherapeutics Inc. | 6 | 2012-01-01 | 2012-04-19 |
| Association Between Smoking, Brain Activity, Genes, and ADHD Cigarette smoking, Abstinence - Smoking, Withdrawal Nicotine | Completed | University of California, Irvine | 89 | 2009-07-01 | 2017-01-13 |
Smoking (5) · Cigarette Smoking (2) · Attention Deficit Disorder with Hyperactivity (1) · Dental Caries (1) · Dental Plaque (1) · Heat Stroke (1) · Inflammation (1) · Motor Activity (1) · Skin Diseases (1) · Tobacco Use (1) · Vaping (1)
Ohio State University Comprehensive Cancer Center (3) · IRCCS San Raffaele (1) · Medical University of Silesia (1) · Philip Morris Products S.A. (1) · Sheba Medical Center (1) · Stealth BioTherapeutics Inc. (1) · Swedish Match AB (1) · Technological Education Institute of Sterea Ellada (1) · University of California, Irvine (1) · University of Rijeka (1)
United States (6) · Greece (2) · Bulgaria (1) · Croatia (1) · Czechia (1) · Germany (1) · Israel (1) · Italy (1) · Japan (1) · Poland (1)
Amit Druyan, M.D (1) · Anna Deltsidou, PhD (1) · Brian E Erkkila, PhD (1) · Brittney L Keller-Hamilton, PhD, MPH (1) · Christelle Haziza, PhD (1) · Francesco Bandello, MD (1) · Jean-G. Gehricke, Ph.D., M.A. (1) · Kenneth C Lasseter, MD (1) · Patrick Tomko, PhD, CSCS (1) · Richard Straube, MD (1) · Theodore L Wagener, PhD (1)
PMID 31156069, PMID 38888700, PMID 39882959
K01DA025131 (1)