83 completed. 83 Phase 2, 9 Phase 1, 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 83 | Completed 83 |
| Phase 1 | 9 | Completed 9 |
| Phase 3 | 5 | Completed 5 |
Follow Chemotherapy: new trials by email Literature Review of Chemotherapy trials Research Report on Chemotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adaptive Therapy for Post-Second-Line Advanced Breast Cancer Gemcitabine, Vinorelbine, or Eribulin - HER2-negative Metastatic Breast Cancer | Phase 2 | Completed | Sun Yat-sen University | 10 | 2024-08-04 | 2025-06-10 |
| Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer Pentoxifylline 400mg plus chemotherapy, Chemotherapy - Breast Cancer Female, Breast Cancer Patients | Phase 2 | Completed | Mansoura University | 100 | 2023-12-25 | 2025-07-28 |
| HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC hepatic arterial infusion chemotherapy (HAIC), Chemotherapy - Intrahepatic Cholangiocarcinoma (Icc) | Phase 2 | Completed | Sun Yat-sen University | 96 | 2023-02-10 | 2025-12-30 |
| A Study of AK112 in Advanced Malignant Tumors AK112, AK117, Chemotherapy - Advanced Malignant Tumors | Phase 1 / Phase 2 | Completed | Akeso | 154 | 2022-01-22 | 2026-03-03 |
| A Study of Canakinumab With Chemotherapy, Radiation Therapy, and Durvalumab in People With Lung Cancer Canakinumab, Durvalumab, Radiation therapy - Non-small Cell Lung Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 41 | 2021-05-21 | 2026-07-08 |
| ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study ABTL0812, Folfirinox, Placebo - Pancreatic Cancer | Phase 1 / Phase 2 | Completed | Ability Pharmaceuticals SL | 150 | 2021-05-06 | 2024-03-18 |
| Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Treatment Esophageal Cancer in Old Age Nimotuzumab, S-1, Concurrent radiation therapy - Esophageal Carcinoma | Phase 2 | Completed | The First Affiliated Hospital with Nanjing Medical University | 56 | 2020-12-01 | 2025-07-04 |
| Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma Durvalumab, Carboplatin, Paclitaxel - Esophageal Squamous Cell Carcinoma | Phase 2 | Completed | Peking Union Medical College Hospital | 60 | 2020-06-19 | 2024-01-22 |
| Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma Pembrolizumab, Carboplatin or Cisplatin, Docetaxel - Esophageal Squamous Cell Carcinoma | Phase 2 | Completed | Peking Union Medical College Hospital | 28 | 2020-06-01 | 2023-10-10 |
| Ultrasound-enhanced Uptake of Chemotherapy in Patients With Inoperable Pancreatic Ductal Adenocarcinoma SonoVue, Chemotherapy - Carcinoma, Pancreatic Ductal | Phase 2 | Completed | St. Olavs Hospital | 20 | 2020-02-10 | 2023-01-19 |
| Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment Metformin plus chemotherapy, Chemotherapy - Metastatic Breast Cancer | Phase 2 | Completed | Hager salah el din | 250 | 2019-10-20 | 2021-12-07 |
| Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ Cancer margetuximab, Retifanlimab, Tebotelimab - Gastric Cancer, Gastroesophageal Junction Cancer | Phase 2 / Phase 3 | Completed | MacroGenics | 82 | 2019-09-30 | 2025-06-08 |
| Chemotherapy w/wo WeiLeShu in Metastatic Colorectal Cancer Weileshu, Chemotherapy - Microbial Colonization, Colorectal Cancer | Phase 2 | Completed | Zhejiang University | 40 | 2019-07-11 | 2023-01-30 |
| Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer Combination drug, Chemotherapy - Pancreatic Cancer | Phase 2 | Completed | Zhejiang University | 110 | 2019-03-27 | 2023-01-27 |
| Improving Outcome of Selected Patients With Non-resectable Hepatic Metastases From Colo-rectal Cancer With Liver Transplantation Liver transplant, Chemotherapy - Liver Metastases, Colorectal Cancer Metastatic | Phase 2 | Completed | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 38 | 2019-01-02 | 2026-10-21 |
| Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma Rogaratinib (BAY1163877), Chemotherapy - Carcinoma, Transitional Cell | Phase 2 / Phase 3 | Completed | Bayer | 175 | 2018-05-31 | 2022-09-28 |
| A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung Cancer Apatinib, chemotherapy - Small-cell Lung Cancer | Phase 2 | Completed | The First Hospital of Jilin University | 31 | 2018-05-31 | 2020-12-01 |
| Hyperthermia Combined With Immunotherapy in the Treatment of Abdominal and Pelvic Malignancies or Metastases Thermotron RF-8, Adoptive cellular Immunotherapy, Anti-PD-1 antibody - Cancer, Abdominal Cancer | Phase 1 / Phase 2 | Completed | Capital Medical University | 40 | 2018-03-01 | 2024-02-07 |
| Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair Defects Pembrolizumab, Chemotherapy - Castration Resistant Prostatic Cancer, Metastatic Prostate Cancer | Phase 2 | Completed | University of California, San Francisco | 26 | 2018-02-20 | 2024-11-20 |
| A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC) TG4010, Chemotherapy, Nivolumab - Non Small Cell Lung Cancer Metastatic | Phase 2 | Completed | Transgene | 44 | 2018-01-05 | 2022-01-11 |
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Carcinoma, Non-Small-Cell Lung (11) · Colorectal Neoplasms (9) · Breast Neoplasms (8) · Lung Neoplasms (6) · Neoplasm Metastasis (6) · Pancreatic Neoplasms (6) · Liver Neoplasms (5) · Glioblastoma (4) · Head and Neck Neoplasms (4) · Neoplasms (4) · Ovarian Neoplasms (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Central Nervous System Neoplasms (3) · Gliosarcoma (3) · Lymphoma (3)
Pfizer (6) · H. Lee Moffitt Cancer Center and Research Institute (2) · Intergroupe Francophone de Cancerologie Thoracique (2) · Light Sciences LLC (2) · National Cancer Institute (NCI) (2) · Peking Union Medical College Hospital (2) · Sun Yat-sen University (2) · Tehran University of Medical Sciences (2) · University of California, San Francisco (2) · University of Florida (2) · Zhejiang University (2) · Ability Pharmaceuticals SL (1) · Aduro Biotech, Inc. (1) · Akeso (1) · Alliance for Clinical Trials in Oncology (1)
United States (42) · China (15) · Spain (10) · France (8) · Germany (8) · Italy (8) · Canada (6) · United Kingdom (6) · Belgium (5) · Poland (5) · South Korea (4) · Czechia (3) · Hungary (3) · Israel (3) · Netherlands (3)
Mark Stanley Berger, MD (2) · Thomas George, MD, FACP (2) · Abi Vainstein, MD (1) · Alain Hendlisz, MD (1) · Alexander Zweibach, MD, PhD (1) · Ardeshir Ghavamzadeh, MD (1) · Bing Hu, MD, PhD (1) · Brigette Ma, MD, FRACP (1) · Burton L. Eisenberg, MD (1) · Cary Presant, MD (1) · David G. Kirsch, MD, PhD (1)
PMID 30062662, PMID 14645425, PMID 15812833, PMID 16135463, PMID 23958375, PMID 24766732, PMID 25582305, PMID 25667281, PMID 25886605, PMID 25908010, PMID 25939894, PMID 26421426, PMID 26782957, PMID 26811178, PMID 27254026, PMID 27538465, PMID 28802565, PMID 30084992, PMID 30137281, PMID 30744591, PMID 30807645, PMID 31126960, PMID 31436322, PMID 32444410, PMID 32451495, PMID 33263418, PMID 33369581, PMID 33581976, PMID 35063281, PMID 35170751, PMID 35293148, PMID 36240478, PMID 36822922, PMID 36995690, PMID 37052821, PMID 40579605, PMID 41164763, PMID 41811823, PMID 42409321, PMID 42844242
2016 (2), 2009 (1), 2014 (1), 2019 (1), P30CA036727 (1), R01CA223484 (1)