10 completed, 8 recruiting, 6 unknown, 4 terminated. 33 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 33 | Completed 10, Recruiting 8, Unknown 6, Terminated 4, Active not recruiting 2, Not yet recruiting 2, Withdrawn 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Chemoradiation: new trials by email Literature Review of Chemoradiation trials Research Report on Chemoradiation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enfortumab Vedotin + Pembrolizumab Induction to Spare the Bladder in MIBC Enfortumab Vedotin, Pembrolizumab, Radiation - Urothelial Bladder Cancer | Phase 2 | Not yet recruiting | The Netherlands Cancer Institute | 56 | 2026-09-01 | 2026-06-25 |
| Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma Biopsy Procedure, Biospecimen Collection, Carboplatin - Sinonasal Squamous Cell Carcinoma, Stage III Sinonasal Cancer AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 108 | 2026-09-01 | 2026-10-05 |
| A Study of Reduced Radiation Therapy With Chemotherapy in People With HPV-Positive Throat Cancer 18F-FMISO PET/CT Scan, Chemoradiation, Questionnaires - Oropharyngeal Carcinoma | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 74 | 2025-05-13 | 2026-05-11 |
| Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer Cisplatin - Oropharyngeal Cancer, Carcinoma | Phase 2 | Recruiting | Zachary Zumsteg | 50 | 2025-05-12 | 2026-08-05 |
| G-CSF After Chemo-radiation in Patients With Glioblastoma Granulocyte Colony Stimulating Factor (G-CSF), Radiation Therapy + Temozolomide - MGMT-Methylated Glioblastoma, Glioblastoma (GBM) | Phase 2 | Recruiting | Massachusetts General Hospital | 60 | 2025-04-02 | 2026-05-05 |
| Primary Chemoradiation VS. Neoadjuvant Chemotherapy Followed By Surgery As Treatment Strategy For LAVC Paclitaxel and Carboplatin, Chemoradiation - Locally Advanced Vulvar Carcinoma, Squamous Cell Carcinoma of the Vulva | Phase 2 | Recruiting | The Netherlands Cancer Institute | 98 | 2024-01-01 | 2024-04-15 |
| Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal Carcinoma Docetaxel, Cis Platinum, 5-FU - Sinonasal Carcinoma | Phase 2 | Not yet recruiting | Dr. Victor H.F. Lee | 30 | 2023-09-01 | 2023-02-28 |
| A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze) Surgery, Chemoradiation, Observation - Oropharyngeal Cancer, Squamous Cell Carcinoma of the Oropharynx | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 150 | 2023-04-27 | 2026-02-02 |
| A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer mFOLFIRINOX, 5-Fluorouracil (5-FU), Oxaliplatin - Pancreatic Cancer, Resectable Pancreatic Cancer | Phase 2 | Terminated | Kimberly Perez, MD | 8 | 2023-01-06 | 2024-12-17 |
| Nivolumab-ipilimumab and Chemoradiation for Cervical Cancer Nivolumab 40 mg in 4 ml Injection, Ipilimumab 200 MG in 40 ML Injection, Chemoradiation - Uterine Cervical Neoplasms | Phase 2 | Recruiting | Hospital Israelita Albert Einstein | 112 | 2022-08-30 | 2024-01-05 |
| Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma Nab-PTX,S-1,Tirelizumab, Chemoradiation - Locally Advanced Gastric Cancer | Phase 2 | Unknown | Zhejiang Cancer Hospital | 33 | 2022-01-01 | 2022-09-06 |
| Neoadjuvant Therapy for Localized Rectal Adenocarcinoma Chemoradiation, short course radiation therapy, mFOLFOX6 - Rectal Adenocarcinoma | Phase 2 | Withdrawn | UNC Lineberger Comprehensive Cancer Center | 2021-08-13 | 2021-11-10 | |
| Study of PD-1 Antibody Combined With Chemoradiotherapy in Oligometastatic Esophageal Cancer PD-1 antibody, Chemoradiation, Albumin-Bound Paclitaxel - Esophagus Cancer, Chemoradiotherapy | Phase 2 | Completed | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 35 | 2020-10-01 | 2025-05-30 |
| Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer Chemoradiotherapy, Ipilimumab, Nivolumab - Rectal Cancer | Phase 2 | Completed | Johannes Laengle, MD, PhD | 80 | 2020-06-01 | 2024-04-23 |
| Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer Nivolumab, Chemoradiation - Oropharynx Cancer | Phase 2 | Completed | UNICANCER | 62 | 2019-07-25 | 2025-03-04 |
| Combination of Chemoradiation With Immunotherapy in Inoperable œsophageal Cancer Nivolumab, Ipilimumab, Chemoradiation - Inoperable œsophageal Cancer | Phase 2 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 8 | 2019-01-17 | 2023-02-21 |
| Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial First-line Chemotherapy, Second-line Chemotherapy, Chemoradiation - Pancreatic Cancer | Phase 2 | Recruiting | Medical College of Wisconsin | 125 | 2018-06-21 | 2026-01-08 |
| Neoadjuvant Chemotherapy Followed by Preoperative Chemoradiation in Resectable Squamous-cell Esophageal Cancer Paclitaxel, Cisplatin, Fluorouracil - Esophageal Neoplasms, Squamous Cell Carcinoma | Phase 2 | Unknown | Mona Frolova | 48 | 2017-07-10 | 2018-07-06 |
| Induction Chemotherapy for Locally Advanced Esophageal Cancer mFOLFOX6, Chemoradiation - Esophageal Carcinoma | Phase 2 | Active not recruiting | University of Rochester | 40 | 2017-06-19 | 2025-09-12 |
| Pembrolizumab and Chemoradiation Treatment for Advanced Cervical Cancer Pembrolizumab, Brachytherapy, Cisplatin - Cervical Cancer | Phase 2 | Completed | Linda R Duska | 94 | 2017-02-09 | 2025-07-03 |
Showing 20 of 33. Sign in to see all of them.
Oropharyngeal Neoplasms (4) · Rectal Neoplasms (4) · Esophageal Neoplasms (3) · Pancreatic Neoplasms (3) · Squamous Cell Carcinoma of Head and Neck (3) · Uterine Cervical Neoplasms (3) · Breast Neoplasms (1) · Carcinoma (1) · Carcinoma, Squamous Cell (1) · Esophageal Squamous Cell Carcinoma (1) · Gallbladder Neoplasms (1) · Glioblastoma (1) · Head and Neck Neoplasms (1) · Pain (1) · Paranasal Sinus Neoplasms (1)
Abramson Cancer Center at Penn Medicine (2) · Tata Memorial Hospital (2) · The Netherlands Cancer Institute (2) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Candel Therapeutics, Inc. (1) · Celgene (1) · Chinese Academy of Medical Sciences (1) · Dr. Victor H.F. Lee (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Hospital Israelita Albert Einstein (1) · Johannes Laengle, MD, PhD (1) · Kimberly Perez, MD (1) · Linda R Duska (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1)
United States (16) · China (3) · France (3) · Brazil (2) · India (2) · Netherlands (2) · Spain (2) · Austria (1) · Canada (1) · Greece (1) · Israel (1) · Italy (1) · Mexico (1) · Norway (1) · Russia (1)
Alexander Lin, MD (1) · Alexey Tryakin, MD, PhD (1) · Charalambos Andreadis, MD (1) · Ehab Y Hanna (1) · Eric Deutsch (1) · Fernando Maluf, MD (1) · Frederic Amant, Prof. (1) · Jing Jin, proffessor (1) · Jorg Dietrich, MD, PhD (1) · Kathleen Christians, MD (1) · Kimberly Perez, MD (1) · Linda Duska, MD (1)
PMID 11398890, PMID 11886723, PMID 16585222, PMID 21166756, PMID 21444871, PMID 22137164, PMID 23874586, PMID 25624177, PMID 26205955, PMID 27461255, PMID 31122213, PMID 31253621, PMID 31953079, PMID 33581976, PMID 38719277, PMID 40844778, PMID 41570275
2018 (2), 2019 (1), UM1CA186712 (1)