15 completed. 15 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 15 |
| Phase 2 | 1 | Completed 1 |
Follow Cefazolin: new trials by email Literature Review of Cefazolin trials Research Report on Cefazolin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis PACK-CXL, Cefazolin in combination with either tobramycin or gentamicin, Cycloplegic agents (cyclopentolate 1% eye drops) - Keratitis; Infectious Disease (Manifestation) | Phase 3 | Completed | University Hospital, Geneva | 35 | 2016-03-01 | 2020-10-20 |
| Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012) Tedizolid Phophate, Antibiotic comparator, Aztreonam - Skin Diseases, Infectious, Skin Diseases, Bacterial | Phase 3 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 120 | 2015-03-25 | 2019-08-07 |
| Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy cephalosporins, Fluoroquinolones, Clindamycin - Kidney Stones | Phase 3 | Completed | Northwell Health | 98 | 2014-09-01 | 2023-09-06 |
| Staphylococcus Aureus Bacteremia Antibiotic Treatment Options Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid - Staphylococcus Aureus Infection | Phase 3 | Completed | Heinrich-Heine University, Duesseldorf | 215 | 2013-12-01 | 2020-05-27 |
| Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) 24-Hour Prophylactic Cefazolin* Antibiotic Regimen, 5-Days Prophylactic Cefazolin* Antibiotic Regimen - Infection, Bone Neoplasms | Phase 3 | Completed | McMaster University | 602 | 2013-01-01 | 2021-03-11 |
| Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane Cefazolin, Clarithromycin - Preterm Premature Rupture of Membrane | Phase 3 | Completed | Samsung Medical Center | 151 | 2011-10-01 | 2022-04-20 |
| Prevention of Arrhythmia Device Infection Trial (PADIT Pilot) Cefazolin, Bacitracin, Cefalexin, Cefazolin - Arrythmias | Phase 3 | Completed | Population Health Research Institute | 500 | 2009-12-01 | 2013-05-16 |
| Effectiveness of Antibiotic Prophylaxis for Totally Implantable Venous Access Device cefazolin Sodium, placebo - Solid Tumor | Phase 3 | Completed | Istanbul University | 150 | 2008-09-01 | 2010-06-02 |
| Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery Cefazolin (Timing of Antibiotic Prophylaxis) - Cesarean Section, Infection | Phase 3 | Completed | MemorialCare | 50 | 2008-08-01 | 2009-09-18 |
| Routine Preoperative Antibiotic Prophylaxis in Modified Radical Mastectomy Cefazolin, Sterile water - Surgical Infection | Phase 3 | Completed | University of the Philippines | 254 | 2007-12-01 | 2012-03-20 |
| Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin Cefazolin, Vancomycin, Amikacin - Nosocomial Neonatal Sepsis | Phase 3 | Completed | Hospital Italiano de Buenos Aires | 109 | 2007-03-01 | 2013-06-03 |
| Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax Ancef or Clindamycin, Placebo - Hemopneumothorax, Pneumothorax | Phase 2 / Phase 3 | Completed | St. Luke's Hospital, Pennsylvania | 50 | 2005-07-01 | 2010-05-21 |
| Antibiotics Study in Preterm Premature Rupture of the Membranes cefazolin, erythromycin, clarithromycin - Preterm Premature Rupture of the Membranes | Phase 3 | Completed | Samsung Medical Center | 101 | 2005-04-01 | 2011-08-08 |
| Comparison of 2 Cefazolin Prophylactic Protocol in Laryngectomy Patients cefazolin - Laryngeal Cancer | Phase 3 | Completed | Tehran University of Medical Sciences | 90 | 2004-06-01 | 2007-05-01 |
| Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department Cefazolin and Moxifloxacin - Cellulitis | Phase 3 | Completed | University of British Columbia | 390 | 2004-01-01 | 2026-04-13 |
Infections (3) · Preterm Premature Rupture of the Membranes (2) · Bone Neoplasms (1) · Cellulitis (1) · Communicable Diseases (1) · Emergencies (1) · Fetal Membranes, Premature Rupture (1) · Hemopneumothorax (1) · Keratitis (1) · Kidney Calculi (1) · Laryngeal Neoplasms (1) · Pneumothorax (1) · Sepsis (1) · Skin Diseases, Bacterial (1) · Skin Diseases, Infectious (1)
Samsung Medical Center (2) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Heinrich-Heine University, Duesseldorf (1) · Hospital Italiano de Buenos Aires (1) · Istanbul University (1) · McMaster University (1) · MemorialCare (1) · Northwell Health (1) · Population Health Research Institute (1) · St. Luke's Hospital, Pennsylvania (1) · Tehran University of Medical Sciences (1) · University Hospital, Geneva (1) · University of British Columbia (1) · University of the Philippines (1)
United States (4) · Canada (3) · Argentina (2) · Netherlands (2) · South Korea (2) · Spain (2) · Australia (1) · Austria (1) · Brazil (1) · Egypt (1) · France (1) · Germany (1) · India (1) · Iran (1) · Philippines (1)
Achim J Kaasch, MD (1) · Dr. Andrew Krahn (1) · Farhad Hafezi, MD, PhD (1) · Hasan Karanlik, MD (1) · Jose M Cernadas, M.D. (1) · Kenneth Chan, MD (1) · Michelle Ghert, MD, FRCSC (1) · Nathaniel McQuay, MD (1) · Nelson C Cabaluna, Doctor of Medicine (1) · Rob Stenstrom, MD (1) · Soo-Young Oh, M.D., PhD (1) · Soo-young Oh, MD, PhD (1) · Zeph Okeke, MD (1)
PMID 21601826, PMID 23052809, PMID 26452342, PMID 30545448, PMID 31806127, PMID 32051007, PMID 32557558, PMID 33395210, PMID 33743753, PMID 33752752, PMID 34859113, PMID 34989778, PMID 34996516, PMID 36746334, PMID 37578113, PMID 38244557
2014 (1)