Comparative Evaluation of Pulp Response to Castor Oil Versus Formocresol as Pulpotomy Medicaments in Primary Teeth :An in Vivo Study
| Registry | NCT05723900 |
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| Status | Completed |
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| Phase | Not applicable |
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| Study type | Interventional; randomized, parallel, masking: double, treatment |
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| Enrollment | 31 (Actual) |
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| Sponsor | Tanta University (Other) |
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| Conditions | Pulp Response to Castor Oil |
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| Interventions | Castor oil, Formocresol (Drug) |
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| Dates | start 2022-09-15, primary completion 2022-10-01, completion 2022-12-15, first posted 2023-02-13, last updated 2023-02-13 |
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| Locations | 1 site in Egypt |
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-Summary
The present study was conducted to evaluate and compare pulp response to Castor oil versus Formocresol as Pulpotomy Medicaments in Primary Teeth
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+Arms and interventions
| Arm | Type | Interventions | Description |
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| Castor oil | Experimental | Drug: Castor oil | Castor oil applied to one side of the selected primary canine |
| Formocresol | Experimental | Drug: Formocresol | Formocresol applied to other side |
- Castor oil (Drug): Procedure :pulpotomy procedure and histological evaluation. A sample of sixty two primary teeth from thirty healthy cooperative children of both sexes who were between 7-9 years and referred to Pediatric Dentistry Department. Two sound teeth without pulpotomy procedure were extracted and subjected to histological procedures to examine the normal pulp tissue and tissue organization (Negative control). The pulpotomy procedure was performed in sixty primary teeth (by split mouth design).
group I treated with castor oil
- Formocresol (Drug): Group II treated with formocresol
+Outcome measures
Primary outcomes
- The degree of pulp inflammation using score. [2 weeks to 3 months]: The degree of pulp inflammation using scores from 0 to 5 , 0 mean no inflammation ,5 mean abscess formation .
Measurement the effect of the castor oil as pulp medicament in treated teeth which subjected to decalcification procedure for histological evaluation under light microscope
- The presence or absence of dentin chips formation by using scores 0 or 1. [2 weeks to 3 months]: The presence or absence of dentin chips formation by using scores 0 or 1.
Measurement the effect of the castor oil as pulp medicament in treated teeth which subjected to decalcification procedure for histological evaluation under light microscope
+Eligibility
Sex: All, ages: 7 Years to 9 Years, accepts healthy volunteers
Inclusion Criteria:
* healthy cooperative children with sound primary canines indicated for extraction for orthodontic reasons
Exclusion Criteria:
* caries primary canines Presence of systemic pathology
+Locations (1)
| Facility | City | Country | Status |
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| Faculty of dentistry | Tanta | Egypt | |
+Investigators
- shomaa Mostafa Hadwa, PHD, Principal investigator, Tanta University