16 completed, 3 recruiting, 3 unknown, 2 active not recruiting. 23 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 16, Recruiting 3, Active not recruiting 2, Unknown 2 |
| Phase 3 | 1 | Terminated 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Calorie restriction: new trials by email Literature Review of Calorie restriction trials Research Report on Calorie restriction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Protein and Polycystic Ovary Syndrome (PCOS) Higher protein dietary pattern, Calorie restriction - Polycystic Ovary Syndrome (PCOS) | Not applicable | Recruiting | University of Arkansas, Fayetteville | 60 | 2025-08-01 | 2025-09-08 |
| Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity Diet Therapy, Calorie Restriction, Behavioral Support - Obesity | Not applicable | Recruiting | University of Alabama at Birmingham | 20 | 2025-08-01 | 2026-04-07 |
| Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial) Intermittent fasting plus time-restricted eating, Calorie restriction - Obesity | Not applicable | Recruiting | Nanfang Hospital, Southern Medical University | 225 | 2024-04-07 | 2024-06-24 |
| Metabolic Impact on the Mitochondria-gut Microbiota Axis of Failure to Follow Restrictive Dietary Interventions in Subjects Living With Obesity Calorie restriction, Intermittent fasting 16/8, Ketogenic diet - Obesity | Not applicable | Completed | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 84 | 2023-04-08 | 2026-03-27 |
| Functional Outcomes From Diets in Multiple Sclerosis Glycemic load, Calorie restriction, Behavioral support - Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis | Not applicable | Active not recruiting | University of Alabama at Birmingham | 100 | 2023-03-20 | 2026-04-03 |
| TRE: Microbiome, Metabolic Health and Bone Time Restricted Eating (TRE), Calorie Restriction - Weight Loss, Time Restricted Feeding | Not applicable | Completed | Rutgers, The State University of New Jersey | 49 | 2022-10-15 | 2026-04-13 |
| Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers Time restricted eating, Calorie Restriction - Time Restricted Eating, Obesity | Not applicable | Active not recruiting | University of Illinois at Chicago | 194 | 2022-05-17 | 2026-07-21 |
| Time Restricted Eating for Weight Management 8-hour Time restricted eating, Calorie restriction - Obesity | Not applicable | Completed | University of Illinois at Chicago | 90 | 2021-01-01 | 2026-07-27 |
| A Comparison Between the Effects of Conventional Diets vs Intermittent Fasting Diabetic and Pre-diabetic Patients Calorie Restriction, Time Restricted Feeding, Time Restricted Feeding with Calorie Restriction - Diabetes Mellitus, Type 2, PreDiabetes | Not applicable | Completed | Usman Bin Hameed | 128 | 2020-09-01 | 2021-06-08 |
| VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men Very Low Calorie Diet, High Intensity Interval Training - Diabetes Mellitus Type 2 in Obese | Not applicable | Completed | University of Nottingham | 21 | 2020-01-01 | 2023-02-16 |
| Intermittent Fasting in Nonalcoholic Fatty Liver Disease Calorie restriction - Intermittent Fasting, Non-Alcoholic Fatty Liver Disease | Not applicable | Unknown | Shaoguan University | 120 | 2018-01-01 | 2020-04-21 |
| Metformin Induces a Dietary Restriction-like State in Human metformin 0.85 twice daily for 6 months, Calorie restriction - Overweight Subjects, Metformin | Phase 4 | Unknown | Xiang Guang-da | 60 | 2016-04-01 | 2016-04-26 |
| The "Metabolically-obese Normal-weight" Phenotype and Its Reversal by Calorie Restriction Calorie restriction - Glucose Metabolism Disorders, Obesity, Visceral | Not applicable | Completed | Singapore Institute of Food and Biotechnology Innovation | 77 | 2016-03-29 | 2018-03-13 |
| Nutrition and Energy Restriction for Cancer Prevention Calorie Restriction - Obesity, Visceral Obesity | Not applicable | Completed | German Cancer Research Center | 150 | 2015-05-01 | 2022-01-13 |
| Calorie Restriction in Multiple Sclerosis Patients Calorie restriction - Multiple Sclerosis | Not applicable | Completed | Washington University School of Medicine | 17 | 2014-02-01 | 2020-05-29 |
| Effects of a Short Term Caloric Restriction on T Cell Activation in Fat Calorie restriction, Activity monitoring, Diet monitoring - Inflammation | Not applicable | Completed | University of Bath | 12 | 2013-01-01 | 2015-06-17 |
| Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS Metformin, Dietary Restriction, Exercise Training - Polycystic Ovary Syndrome | Phase 3 | Terminated | Pennington Biomedical Research Center | 32 | 2012-05-01 | 2022-03-15 |
| Calorie Restriction Retards the Aging Process energy restricted mediterranean-type diet, 25 % calorie restriction - Obesity | Not applicable | Unknown | University of Chile | 48 | 2012-05-01 | 2012-10-23 |
| Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery calorie restriction - Acute Renal Failure | Not applicable | Completed | University of Cologne | 82 | 2012-01-01 | 2019-08-09 |
| Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults Calorie Restriction, Control (normal living) - Insulin Resistance | Not applicable | Completed | Mayo Clinic | 29 | 2011-12-01 | 2014-11-26 |
Showing 20 of 25. Sign in to see all of them.
Obesity (13) · Weight Loss (6) · Intermittent Fasting (5) · Insulin Resistance (4) · Obesity, Abdominal (3) · Diabetes Mellitus (2) · Polycystic Ovary Syndrome (2) · Acute Kidney Injury (1) · Body Weight (1) · Bone Diseases, Metabolic (1) · Colorectal Neoplasms (1) · Coronary Disease (1) · Diabetes Mellitus, Type 2 (1) · Fasting (1) · Glucocorticoid Receptor Deficiency (1)
University of Illinois at Chicago (3) · University of Alabama at Birmingham (2) · Washington University School of Medicine (2) · German Cancer Research Center (1) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (1) · Mayo Clinic (1) · Nanfang Hospital, Southern Medical University (1) · Pennington Biomedical Research Center (1) · Rutgers, The State University of New Jersey (1) · Shaoguan University (1) · Singapore Institute of Food and Biotechnology Innovation (1) · St. Louis University (1) · Tufts University (1) · University of Arkansas, Fayetteville (1) · University of Bath (1)
United States (14) · China (3) · Germany (2) · United Kingdom (2) · Chile (1) · Mexico (1) · Pakistan (1)
Krista Varady, PhD (2) · Anne H Cross, MD (1) · Brooks Wingo, PhD (1) · Dylan Thompson, PhD (1) · Edward P Weiss, PhD (1) · Faidon Magkos, PhD (1) · Guangda Xiang, MD,PhD (1) · Huijie Zhang, MD. PhD. (1) · Iskandar Idris, BMBS FRCP DM (1) · K. Sreekumaran Nair, M.D., Ph.D. (1) · Laura A Velazquez Villegas, PhD (1) · Laura Piccio, MD, PhD (1) · Leanne M Redman, PhD (1) · Lisa Tussing-Humphreys, PhD, MS, RD (1) · Marc Hellerstein, MD, PhD (1)
PMID 33512717, PMID 25877812, PMID 27465384, PMID 27580151, PMID 28323951, PMID 28459931, PMID 29258678, PMID 29535139, PMID 29676049, PMID 29874567, PMID 30252100, PMID 30297199, PMID 30377436, PMID 30475957, PMID 31328895, PMID 33358713, PMID 35287713, PMID 37364268, PMID 38798539, PMID 38821260
K01DK080886 (1), P30DK079626 (1), R00HD060762 (1), R01CA257807 (1), R01DK128180 (1), R01HL106228 (1)