5 completed, 1 recruiting, 1 withdrawn. 7 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow brodalumab: new trials by email Literature Review of brodalumab trials Research Report on brodalumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Brodalumab in the Treatment of Immune-Related Adverse Events Brodalumab, CT scan - Breast Cancer, Esophageal Cancer | Phase 1 | Recruiting | Brian Henick, MD | 11 | 2025-03-11 | 2026-05-13 |
| A Study of KHK4827 in Patients With Systemic Sclerosis KHK4827 - Systemic Sclerosis | Phase 1 | Completed | Kyowa Kirin Co., Ltd. | 8 | 2017-10-06 | 2025-07-11 |
| A Bioequivalence Study Comparing a Single 1.5mL Dose of Brodalumab vs. Two Doses (1.0mL + 0.5mL) of Brodalumab Brodalumab - Psoriasis | Phase 1 | Completed | Bausch Health Americas, Inc. | 145 | 2014-09-01 | 2017-06-20 |
| Brodalumab Drug-Drug Interaction (DDI) and Intensive Pharmacodynamic (PK) Study in Psoriasis Subjects Brodalumab - Psoriasis | Phase 1 | Completed | Bausch Health Americas, Inc. | 31 | 2013-09-01 | 2017-04-10 |
| A Clinical Pharmacology of KHK4827 in Healthy Volunteers and Subject With Moderate to Severe Psoriasis Placebo, KHK4827 - Psoriasis | Phase 1 | Completed | Kyowa Kirin Co., Ltd. | 48 | 2011-11-01 | 2012-11-02 |
| Safety, Tolerability, and Pharmacokinetics of AMG 827 in Adolescents With Asthma AMG 827 or Placebo - Asthma | Phase 1 | Withdrawn | Amgen | 2011-06-01 | 2013-11-25 | |
| Study to Evaluate the Safety, PK, PD and Efficacy of AMG 827 in Adults With Rheumatoid Arthritis Brodalumab, Placebo - Rheumatoid Arthritis | Phase 1 / Phase 2 | Completed | Amgen | 40 | 2008-10-27 | 2021-11-26 |
Psoriasis (3) · Arthritis, Rheumatoid (1) · Asthma (1) · Brain Neoplasms (1) · Breast Neoplasms (1) · Colonic Neoplasms (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Kidney Neoplasms (1) · Liver Neoplasms (1) · Lung Neoplasms (1) · Mouth Neoplasms (1) · Pancreatic Neoplasms (1) · Prostatic Neoplasms (1) · Rectal Neoplasms (1)
Amgen (2) · Bausch Health Americas, Inc. (2) · Kyowa Kirin Co., Ltd. (2) · Brian Henick, MD (1)
United States (3) · Japan (2) · Australia (1) · New Zealand (1)
Brian Henick, MD (1)