3 completed, 3 terminated, 2 unknown, 1 enrolling by invitation. 10 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 3, Terminated 3, Unknown 2, Enrolling by invitation 1, Not yet recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Betahistine: new trials by email Literature Review of Betahistine trials Research Report on Betahistine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine - Tinnitus | Phase 2 | Enrolling by invitation | Leading Edge Clinic | 20 | 2026-05-15 | 2026-05-13 |
| Efficacy and Safety of Rimegepant for Acute Dizziness Rimegepant 75mg Orally Disintegrating Tablets (ODT), Betahistine Mesylate tablet - Dizziness | Phase 2 / Phase 3 | Not yet recruiting | Shi Tianming | 370 | 2026-03-20 | 2026-02-27 |
| Modulating Auditory Symptoms and Vertigo of Meniere's Disease by Non-invasive Mastoid Electric Stimulation YPS-201b, betahistine - Meniere's Disease | Phase 1 / Phase 2 | Unknown | Seoul National University Hospital | 120 | 2023-09-18 | 2024-12-05 |
| Laser Acupuncture for Meniere Disease Multiwave Locked System (MLS) laser (Mphi laser, ASA Srl, Vicenza, Italy), Betahistine Mesylate tablet - Meniere Disease | Phase 2 | Unknown | Beijing Tongren Hospital | 324 | 2021-05-01 | 2024-08-09 |
| Efficacy Study of Betahistine on Body Weight in Obese Female Subjects betahistine dihydrochloride, placebo - Obesity | Phase 2 | Completed | OBEcure Ltd. | 187 | 2008-09-01 | 2009-05-07 |
| Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain Betahistine, Placebo Oral Tablet - Schizophrenia, Schizoaffective Disorder | Phase 2 | Completed | Nathan Kline Institute for Psychiatric Research | 48 | 2008-07-01 | 2019-01-25 |
| Pilot Study of Betahistine Dihydrochloride in the Treatment of Major Depression With Atypical Features betahistine dihydrochloride - Recurrent Major Depressive Disorder With Atypical Features | Phase 2 | Terminated | University of Cincinnati | 1 | 2007-07-01 | 2017-07-25 |
| A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Effect of Betahistine on Plasma Lipids in Patients Treated With Simvastatin Betahistine - Hypercholesterolemia | Phase 2 | Terminated | OBEcure Ltd. | 30 | 2007-05-01 | 2007-09-26 |
| Study to Examine the Effect of Betahistine on Body Weight Gain Due to Olanzapine Treatment Betahistine - Weight Gain | Phase 2 | Terminated | OBEcure Ltd. | 36 | 2007-03-01 | 2015-10-15 |
| The Effect of Betahistine on Body Weight in Obese Subjects Betahistine, Dietary counseling - Obesity | Phase 2 | Completed | OBEcure Ltd. | 280 | 2007-01-01 | 2015-04-21 |
Obesity (3) · Meniere Disease (2) · Schizophrenia (2) · Autism Spectrum Disorder (1) · Depression (1) · Dizziness (1) · Hypercholesterolemia (1) · Post-Acute COVID-19 Syndrome (1) · Psychotic Disorders (1) · Tinnitus (1) · Weight Gain (1) · Weight Loss (1)
OBEcure Ltd. (4) · Beijing Tongren Hospital (1) · Leading Edge Clinic (1) · Nathan Kline Institute for Psychiatric Research (1) · Seoul National University Hospital (1) · Shi Tianming (1) · University of Cincinnati (1)
United States (4) · Israel (2) · Belgium (1) · Canada (1) · China (1) · Germany (1) · Netherlands (1) · South Korea (1)
Nir Barak, MD (2) · Ami Eyal, MD (1) · Andrew Ahmann, MD (1) · Dean Kereiakes, MD (1) · Diane Krieger, MD (1) · Diane Smith, MD (1) · Erik Nelson, MD (1) · Frank Greenway, MD (1) · Harold Bays, MD (1) · James Zavoral, MD (1) · Jeffrey Geohas, MD (1) · Ken Fujioka, MD (1) · Lisa Wright, MD (1) · Louis Aronne, MD (1) · Luc Van Gaal, MD Professor (1)
2008 (1)