7 completed, 4 unknown, 2 terminated, 1 withdrawn. 3 Phase 1, 3 Phase 3, 3 Phase 4, 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Not applicable | 2 | Unknown 2 |
| Phase 2 | 2 | Completed 2 |
| Early Phase 1 | 1 | Unknown 1 |
Follow beraprost: new trials by email Literature Review of beraprost trials Research Report on beraprost
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Protective Effect of Beraprost Sodium Tablets on Reperfusion Therapy for Acute STEMI Beraprost Sodium Tablets - Essential Hypertension | Early Phase 1 | Unknown | Shenzhen People's Hospital | 100 | 2022-05-01 | 2022-02-08 |
| A Study With BPS-314d-MR-PAH-303 in Participants With Pulmonary Arterial Hypertension Esuberaprost, Placebo - Pulmonary Arterial Hypertension | Phase 3 | Terminated | Lung Biotechnology PBC | 112 | 2018-12-10 | 2020-09-07 |
| Evaluation of Nail Fold Microcirculation in CKD Alprostadil Injection, Beraprost sodium tablets - Chronic Renal Disease | Phase 4 | Unknown | The Affiliated Hospital of Xuzhou Medical University | 100 | 2018-02-01 | 2018-09-26 |
| Effect of Beraprost Sodium (Berasil) on Hemodialysis Beraprost sodium (Berasil) - Arteriovenous Fistula Patency | Not applicable | Unknown | Yonsei University | 60 | 2017-04-05 | 2018-05-18 |
| Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children Beraprost Sodium, Sildenafil Citrate - Pediatric Pulmonary Hypertension | Phase 4 | Completed | Dr. Soetomo General Hospital | 40 | 2017-04-01 | 2018-02-13 |
| Compassionate Use of Beraprost Sodium 314d Modified Release for Patients With Pulmonary Arterial Hypertension (PAH) BPS-314d-MR - Pulmonary Arterial Hypertension | Phase 2 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 1 | 2013-11-01 | 2020-10-20 |
| Beraprost-314d Added-on to Tyvaso® (BEAT) Beraprost Sodium 314d Modified Release Tablets, Placebo - Pulmonary Arterial Hypertension | Phase 3 | Completed | Lung Biotechnology PBC | 273 | 2013-05-31 | 2020-08-03 |
| Beraprost Sodium and Arterial Stiffness in Patients With Type 2 Diabetic Nephropathy Beraprost sodium - Diabetic Nephropathy | Not applicable | Unknown | Seoul National University Hospital | 102 | 2013-03-01 | 2013-12-16 |
| A Multinational, Multicenter, Study to Assess the Efficacy and Safety of BPS-314d-MR in Subjects With Pulmonary Arterial Hypertension Currently Receiving Treatment With an Endothelin Receptor Antagonist and/or a Phosphodiesterase-5 Inhibitor Beraprost Sodium 314d Modified Release Tablets, Placebo - Pulmonary Arterial Hypertension | Phase 3 | Withdrawn | Lung Biotechnology PBC | 2011-11-01 | 2012-05-14 | |
| A Pharmacokinetic Study of TRK-100STP in Japanese Patients With Renal Impairment beraprost sodium(BPS) - Renal Impairment | Phase 1 | Completed | Toray Industries, Inc | 24 | 2011-08-01 | 2014-03-04 |
| Study to Compare Pharmacokinetic Profiles of TRK-100STP in Japanese, Chinese, and South Korean Non-elderly Healthy Adult Males TRK-100STP - Healthy Adult Male, Pharmacokinetics of TRK-100-STP | Phase 1 | Completed | Astellas Pharma Inc | 36 | 2011-08-01 | 2011-10-04 |
| Efficacy and Safety of Dorner Tablets and Aspirin for Prevention of Arteriosclerosis Progress in Type 2 Diabetes Mellitus Patients Beraprost, Aspirin - Type 2 Diabetes Mellitus | Phase 4 | Terminated | Astellas Pharma Inc | 190 | 2010-07-01 | 2016-06-21 |
| Drug-Drug Interaction Study of TRK-100STP TRK-100STP (BERASUS LA), AST-120 (Kremezin®) - Healthy | Phase 1 | Completed | Astellas Pharma Inc | 24 | 2008-06-01 | 2008-10-13 |
| TRK-100STP PhaseII Clinical Study -Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis) Beraprost, Placebo - Renal Insufficiency, Chronic | Phase 2 | Completed | Toray Industries, Inc | 113 | 2005-10-01 | 2015-06-29 |
Pulmonary Arterial Hypertension (4) · Renal Insufficiency, Chronic (2) · Arteriosclerosis (1) · Cardiovascular Diseases (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Nephropathies (1) · Essential Hypertension (1) · Familial Primary Pulmonary Hypertension (1) · Hypertension (1) · Hypertension, Pulmonary (1) · Kidney Failure, Chronic (1) · Lung Diseases (1) · Nephrosclerosis (1) · Renal Insufficiency (1) · Respiratory Tract Diseases (1)
Astellas Pharma Inc (3) · Lung Biotechnology PBC (3) · Toray Industries, Inc (2) · Dr. Soetomo General Hospital (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Seoul National University Hospital (1) · Shenzhen People's Hospital (1) · The Affiliated Hospital of Xuzhou Medical University (1) · Yonsei University (1)
China (3) · Japan (3) · United States (3) · Israel (2) · South Korea (2) · Indonesia (1)
Chun-Soo Lim, Prof (1) · Dong Ki Kim, Prof (1) · Dong Sun, MD (1) · Ki Young Na, Prof (1) · Mahrus Rachman, MD (1) · Ronald J Oudiz, MD (1) · Sung Gyun Kim, Prof (1) · Young-Ki Lee, Prof (1)