9 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 14 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 9, Terminated 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 5 | Completed 3, Terminated 1, Unknown 1 |
Follow Ampicillin: new trials by email Literature Review of Ampicillin trials Research Report on Ampicillin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prophylactic Antibiotic Duration in Head and Neck Cancer Surgery (PROTECT-HN Trial) Ampicillin/Sulbactam 24-Hour Postoperative Prophylaxis, Ampicillin/Sulbactam 7-Day Postoperative Prophylaxis - Surgical Wound Infection, Head and Neck Neoplasms | Phase 3 | Recruiting | AC Camargo Cancer Center | 80 | 2025-05-29 | 2026-10-05 |
| NICU Antibiotics and Outcomes (NANO) Follow-up Study Ampicillin, Gentamicin, Placebo - Premature Birth, Antibiotics | Phase 3 | Not yet recruiting | Sharp HealthCare | 802 | 2024-04-01 | 2023-08-04 |
| Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition Ceftriaxone Sodium, Ampicillin, Gentamicin - HIV-1-infection, Malnutrition, Child | Phase 2 / Phase 3 | Unknown | Makerere University | 300 | 2021-06-14 | 2021-09-30 |
| A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia Benzyl penicillin, Gentamicin Sulfate, Ceftriaxone - Pneumonia | Phase 3 | Completed | University of Oxford | 4392 | 2019-08-19 | 2024-07-08 |
| Treatment of ppROM With Erythromycin vs. Azithromycin Trial Azithromycin, Erythromycin, Ampicillin - Preterm Premature Rupture of Membranes (PPROM) | Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 21 | 2017-02-23 | 2024-06-25 |
| Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae Antipseudomonal beta-lactam antibiotic, De-escalation(short-spectrum antibiotic) - Enterobacteriaceae Infections | Phase 3 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 344 | 2016-10-01 | 2020-07-17 |
| Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia Solithromycin, Standard of Care - Community-acquired Bacterial Pneumonia | Phase 2 / Phase 3 | Terminated | Melinta Therapeutics, Inc. | 97 | 2016-04-01 | 2019-01-03 |
| Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy cephalosporins, Fluoroquinolones, Clindamycin - Kidney Stones | Phase 3 | Completed | Northwell Health | 98 | 2014-09-01 | 2023-09-06 |
| Antibiotic Safety (SCAMP) ampicillin and metronidazole and gentamicin, ampicillin and gentamicin and clindamycin, gentamicin and Piperacillin- tazobactam - Complicated Intra Abdominal Infections | Phase 2 / Phase 3 | Completed | Michael Cohen-Wolkowiez | 260 | 2013-12-01 | 2019-05-30 |
| Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis Meropenem, Ampicillin + gentamicin or cefotaxime + gentamicin - Sepsis | Phase 3 | Completed | PENTA Foundation | 272 | 2012-09-01 | 2015-02-16 |
| The Study of Unasyn-S 12g/Day for Community Acquired Pneumonia (CAP) ampicillin sodium/sulbactam sodium - Pneumonia, Bacterial | Phase 3 | Completed | Pfizer | 47 | 2010-10-01 | 2012-07-13 |
| Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis Unasyn, Ampicillin/gentamicin - Chorioamnionitis | Phase 2 / Phase 3 | Completed | Stanford University | 92 | 2009-05-01 | 2018-05-18 |
| Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Ampicillin + gentamicin - Chorioamnionitis, Puerperal Endometritis | Phase 2 / Phase 3 | Completed | Hospital de Santa Maria, Portugal | 161 | 2008-10-01 | 2016-11-28 |
| Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission Erythromycin, Nevirapine, Ampicillin sodium - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 3720 | 2021-11-01 |
Chorioamnionitis (3) · Pneumonia (2) · Sepsis (2) · Bacteremia (1) · Child Nutrition Disorders (1) · Community-Acquired Pneumonia (1) · Endometritis (1) · Enterobacteriaceae Infections (1) · Fetal Membranes, Premature Rupture (1) · HIV Infections (1) · Head and Neck Neoplasms (1) · Intraabdominal Infections (1) · Kidney Calculi (1) · Neonatal Sepsis (1) · Pharyngeal Neoplasms (1)
AC Camargo Cancer Center (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Hospital de Santa Maria, Portugal (1) · Makerere University (1) · Melinta Therapeutics, Inc. (1) · Michael Cohen-Wolkowiez (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Northwell Health (1) · PENTA Foundation (1) · Pfizer (1) · Sharp HealthCare (1) · Stanford University (1) · The University of Texas Medical Branch, Galveston (1) · University of Oxford (1)
United States (7) · Canada (2) · Spain (2) · Brazil (1) · Bulgaria (1) · Hungary (1) · Italy (1) · Japan (1) · Kenya (1) · Philippines (1) · Portugal (1) · Uganda (1) · United Kingdom (1)
Ambrose Agweyu, PhD (1) · Anup Katheria, MD (1) · Filipa Faria Vaz Passos, Dr (1) · Irja Lutsar (1) · Jean-Pierre Aboulker (1) · Luis Eduardo Lopez Cortes, MD, PhD (1) · Michael Cohen-Wolkowiez, MD, PhD (1) · Micheal Cohen-Wolkowiez, MD, PhD (1) · Natali Aziz, MD (1) · Nkechinyere Emezienna, MD (1) · Robert Goldenberg, MD (1) · Taha E Taha, MD, PhD (1) · Ursula Trafojer (1) · Zeph Okeke, MD (1)
PMID 16227794, PMID 16522393, PMID 16875654, PMID 17267841, PMID 17978109, PMID 19664210, PMID 23090521, PMID 24102758, PMID 25533886, PMID 28601833, PMID 33902072, PMID 35813373, PMID 37578113, PMID 38215770