4 completed, 1 unknown. 5 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Amantadine: new trials by email Literature Review of Amantadine trials Research Report on Amantadine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TCAD vs. Monotherapy for Influenza A in Immunocompromised Patients TCAD, Zanamivir or Oseltamivir, Open label treatment with TCAD - Influenza | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 7 | 2009-03-01 | 2013-08-15 |
| Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With Amantadine amantadine hydrochloride, oseltamivir phosphate - Healthy | Phase 1 | Completed | Novartis | 18 | 2006-08-01 | 2007-11-30 |
| Study of Amantadine for Weight Stabilization During Olanzapine Treatment Olanzapine, Amantadine, Olanzapine and placebo - Psychotic Disorder, Schizophreniform Disorder | Phase 1 | Completed | University of North Carolina, Chapel Hill | 40 | 2005-05-01 | 2011-05-02 |
| Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia, Opioid Use, and Pain After Radical Prostatectomy Amantadine - Hyperalgesia, Pain | Phase 1 / Phase 2 | Unknown | University Health Network, Toronto | 132 | 2004-01-01 | 2006-03-14 |
| Prepulse Inhibition of Startle in Cocaine Dependence - 7 Amantadine - Cocaine-Related Disorders, Substance-Related Disorders | Phase 1 | Completed | National Institute on Drug Abuse (NIDA) | 1997-02-01 | 2017-01-12 |
Cocaine-Related Disorders (1) · Hyperalgesia (1) · Influenza, Human (1) · Pain (1) · Prostatic Neoplasms (1) · Psychotic Disorders (1) · Schizophrenia (1) · Substance-Related Disorders (1)
Fred Hutchinson Cancer Center (1) · National Institute on Drug Abuse (NIDA) (1) · Novartis (1) · University Health Network, Toronto (1) · University of North Carolina, Chapel Hill (1)
United States (4) · Canada (1)
John Rotrosen, M.D. (1) · Karen A Graham, MSc MD (1) · Lucia Gagliese, PhD (1) · Michael Boeckh, MD (1)