3 completed, 1 terminated, 1 unknown. 5 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Terminated 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Tympanic Membrane Perforation: new trials by email Literature Review of Tympanic Membrane Perforation trials Research Report on Tympanic Membrane Perforation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations FGF-2, Placebo - Tympanic Membrane Perforation | Phase 2 | Completed | NYU Langone Health | 52 | 2022-05-27 | 2026-04-13 |
| Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing. Manukamed - Manukapli 100% sterile honey wound dressing - Premium medical grade 16+ Leptospermum Scoparium New Zealand honey - Otitis Media, Suppurative, Tympanic Membrane Perforation | Phase 2 / Phase 3 | Completed | Fakultas Kedokteran Universitas Indonesia | 64 | 2021-06-13 | 2022-11-04 |
| Use of Autologous Plasma Rich in Platelets and Extracellular Vesicles in the Surgical Treatment of Chronic Middle Ear Infections Platelet- and extracellular vesicle-rich plasma, Control group - Otitis Media Chronic, Tympanic Membrane Perforation | Phase 2 / Phase 3 | Unknown | University Medical Centre Ljubljana | 100 | 2021-02-14 | 2021-02-21 |
| Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation Platelet Rich Plasma - Tympanic Membrane Perforation | Phase 1 / Phase 2 | Terminated | University of Kansas Medical Center | 1 | 2018-05-02 | 2024-07-16 |
| Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations FGF-2, Placebo - Tympanic Membrane Perforation | Phase 2 | Completed | D. Bradley Welling, MD, PhD | 57 | 2016-10-01 | 2025-12-08 |
Hearing Loss (1) · Otitis Media, Suppurative (1)
Ear Diseases (5) · Otorhinolaryngologic Diseases (5) · Wounds and Injuries (5) · Hearing Disorders (1) · Infections (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Otitis (1) · Otitis Media (1) · Pathological Conditions, Signs and Symptoms (1) · Sensation Disorders (1) · Signs and Symptoms (1) · Suppuration (1)
Fibroblast Growth Factor 2 (2) · Control Groups (1) · Platelet Count (1)
D. Bradley Welling, MD, PhD (1) · Fakultas Kedokteran Universitas Indonesia (1) · NYU Langone Health (1) · University Medical Centre Ljubljana (1) · University of Kansas Medical Center (1)
United States (3) · Indonesia (1) · Slovenia (1)
D. B. Welling, M.D., Ph.D (1) · David Friedmann, MD (1) · Harim Priyono (1) · Hinrich Staecker, MD (1)