3 completed. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
Follow Tuberous Sclerosis Complex: new trials by email Literature Review of Tuberous Sclerosis Complex trials Research Report on Tuberous Sclerosis Complex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants TAVT-18 (sirolimus) - Tuberous Sclerosis Complex, Epilepsy | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 5 | 2020-09-08 | 2024-05-16 |
| Safety of Simvastatin in LAM and TSC Simvastatin, Sirolimus Oral Product, Everolimus Oral Product - Lymphangioleiomyomatosis, Tuberous Sclerosis Complex | Phase 1 / Phase 2 | Completed | University of Pennsylvania | 10 | 2014-03-01 | 2020-08-25 |
| Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC) Everolimus - Epilepsy, Tuberous Sclerosis Complex | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 20 | 2010-01-01 | 2017-03-13 |
Tuberous Sclerosis (3) · Epilepsy (2) · Hereditary Sensory and Autonomic Neuropathies (1) · Lymphangioleiomyomatosis (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hamartoma (3) · Heredodegenerative Disorders, Nervous System (3) · Malformations of Cortical Development (3) · Malformations of Cortical Development, Group I (3) · Neoplasms (3) · Neoplasms, Multiple Primary (3) · Neoplastic Syndromes, Hereditary (3) · Nervous System Diseases (3) · Nervous System Malformations (3) · Neurocutaneous Syndromes (3) · Neurodegenerative Diseases (3) · Brain Diseases (2)
Everolimus (2) · Sirolimus (2) · Simvastatin (1)
Children's Hospital Medical Center, Cincinnati (2) · University of Pennsylvania (1)
United States (3)
Darcy Krueger, M.D. Ph.D (1) · Darcy Krueger, MD, PhD (1) · Frank McCormack, MD (1) · Maryl Kreider, MD, MSCE (1) · Vera P Krymskaya, PhD, MBA (1)