7 completed. 7 Phase 2, 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 3 | 5 | Completed 5 |
Follow Trypanosomiasis, African: new trials by email Literature Review of Trypanosomiasis, African trials Research Report on Trypanosomiasis, African
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients Acoziborole - Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 35 | 2022-07-09 | 2026-04-06 |
| Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects Acoziborole, Placebo - Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 1208 | 2021-12-30 | 2025-03-20 |
| Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense Fexinidazole - Trypanosomiasis, African, Sleeping Sickness | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 45 | 2019-09-29 | 2025-01-30 |
| Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense Acoziborole - Trypanosomiasis, African, Gambiense Trypanosomiasis | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 208 | 2016-10-11 | 2025-09-17 |
| Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2 Fexinidazole, Nifurtimox, Eflornithine - Human African Trypanosomiasis (HAT), Sleeping Sickness | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 394 | 2012-10-01 | 2018-02-20 |
| Trial of DB289 for the Treatment of Stage I African Trypanosomiasis DB289, Pentamidine - African Trypanosomiasis | Phase 2 | Completed | Immtech Pharmaceuticals, Inc | 111 | 2003-02-01 | 2008-12-08 |
| A Trial of DB289 for the Treatment of Stage I African Trypanosomiasis DB289 - Trypanosomiasis, African | Phase 2 | Completed | Immtech Pharmaceuticals, Inc | 30 | 2001-08-01 | 2008-12-05 |
Infections (3) · Neglected Diseases (1)
Euglenozoa Infections (7) · Parasitic Diseases (7) · Protozoan Infections (7) · Trypanosomiasis (7) · Vector Borne Diseases (7) · Infections (4) · Disease Attributes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
fexinidazole (2) · Eflornithine (1) · Nifurtimox (1) · Pentamidine (1) · SCYX 7158 (1)
Drugs for Neglected Diseases (5) · Immtech Pharmaceuticals, Inc (2)
Democratic Republic of the Congo (4) · Guinea (3) · Republic of the Congo (3) · Angola (1) · Central African Republic (1) · Malawi (1) · Uganda (1)
Christian Burri, MSc, PhD (1) · Enock Matovu, Prof (1) · Victor Kande Betu Kumeso, Dr (1) · Victor Kande Betu Kumeso, Dr. (1) · Victor Kande, MD (1)