10 completed, 1 unknown. 7 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 7 |
| Phase 2 | 7 | Completed 6, Unknown 1 |
Follow T-cell Adult Acute Lymphoblastic Leukemia: new trials by email Literature Review of T-cell Adult Acute Lymphoblastic Leukemia trials Research Report on T-cell Adult Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter Study of Risk-adapted Treatment for T-lineage ALL of Young Adults (18-59 Years Old) nelarabine - T-cell Adult Acute Lymphoblastic Leukemia | Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 275 | 2015-12-01 | 2019-10-21 |
| Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults MLN 9708, Vincristine, Cytarabine - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 1 | Completed | Massachusetts General Hospital | 19 | 2014-12-01 | 2019-11-26 |
| CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma 6,8-bis(benzylthio)octanoic acid, bendamustine hydrochloride - Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Predominant Hodgkin Lymphoma | Phase 1 | Completed | Wake Forest University Health Sciences | 16 | 2014-09-01 | 2024-02-13 |
| Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant tetanus-CMV fusion peptide vaccine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | City of Hope Medical Center | 36 | 2012-10-29 | 2024-04-02 |
| Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Akt inhibitor MK2206, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2010-12-01 | 2020-11-04 |
| Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma panobinostat, everolimus, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 124 | 2009-06-01 | 2020-03-10 |
| Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma L-asparaginase, doxorubicin hydrochloride, therapeutic hydrocortisone - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 148 | 2009-03-01 | 2017-01-27 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| 7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes 7-hydroxystaurosporine, perifosine, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Megakaryoblastic Leukemia (M7) | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2005-12-01 | 2013-09-30 |
| Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia allopurinol, cyclophosphamide, daunorubicin hydrochloride - Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 302 | 2003-06-01 | 2022-05-03 |
| Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation therapeutic allogeneic lymphocytes, aldesleukin, peripheral blood stem cell transplantation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2002-09-01 | 2017-03-29 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (10) · Lymphoma, Extranodal NK-T-Cell (5) · Lymphoma, Large-Cell, Anaplastic (5) · Lymphoma, T-Cell, Cutaneous (5) · Mycosis Fungoides (5) · Sezary Syndrome (5) · Congenital Abnormalities (4) · Hodgkin Disease (4) · Leukemia, Large Granular Lymphocytic (4) · Leukemia, Lymphocytic, Chronic, B-Cell (4) · Leukemia, Myeloid, Acute (4) · Lymphoma, B-Cell, Marginal Zone (4) · Lymphoma, Follicular (4) · Lymphoma, Large B-Cell, Diffuse (4) · Lymphoma, Mantle-Cell (4)
Hematologic Diseases (10) · Hemic and Lymphatic Diseases (10) · Immune System Diseases (10) · Immunoproliferative Disorders (10) · Leukemia (10) · Leukemia, Lymphoid (10) · Lymphatic Diseases (10) · Lymphoproliferative Disorders (10) · Neoplasms (10) · Neoplasms by Histologic Type (10) · Chronic Disease (6) · Disease Attributes (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Hemorrhagic Disorders (5)
Cyclophosphamide (4) · Cytarabine (3) · Methotrexate (3) · Vincristine (3) · Asparaginase (2) · Cytogenetic Analysis (2) · Doxorubicin (2) · Filgrastim (2) · Flow Cytometry (2) · Leucovorin (2) · Mercaptopurine (2) · merphos (2) · 7-hydroxystaurosporine (1) · Acyclovir (1) · Alemtuzumab (1)
National Cancer Institute (NCI) (4) · Assistance Publique - Hôpitaux de Paris (1) · Case Comprehensive Cancer Center (1) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Center (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · Wake Forest University Health Sciences (1)
United States (10) · Australia (1) · Canada (1) · France (1) · Puerto Rico (1)
Brenda Cooper, MD (1) · Ivana Gojo (1) · Merav Bar (1) · Philip Amrein, MD (1) · Rakhee Vaidya (1) · Ryotaro Nakamura (1) · Shaji Kumar (1) · Terzah Horton, MD PhD (1) · Wendy Stock (1) · Yasuhiro Oki (1)
PMID 23443507, PMID 26213141, PMID 26853648, PMID 28419486, PMID 30562587, PMID 30957229, PMID 41135009
N01CM00039 (1), N01CM62202 (1), P01CA018029 (1), P30CA012197 (1), P30CA015083 (1), P30CA016672 (1), U10CA031946 (1), U10CA098543 (1), U10CA180886 (1)