5 completed, 2 terminated. 5 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 3, Terminated 2 |
| Phase 2 | 5 | Completed 4, Terminated 1 |
Follow Stage II Small Lymphocytic Lymphoma: new trials by email Literature Review of Stage II Small Lymphocytic Lymphoma trials Research Report on Stage II Small Lymphocytic Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas lenalidomide, etoposide, prednisone - Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | University of Chicago | 55 | 2014-07-29 | 2026-03-11 |
| Cyclophosphamide, Alvocidib, and Rituximab in Treating Patients With High Risk B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Alvocidib Hydrochloride, Cyclophosphamide, Diagnostic Laboratory Biomarker Analysis - Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 9 | 2010-04-01 | 2015-11-11 |
| Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Cyclophosphamide, Laboratory Biomarker Analysis, Ofatumumab - Chronic Lymphocytic Leukemia, Stage 0 Chronic Lymphocytic Leukemia | Phase 2 | Completed | Mayo Clinic | 82 | 2010-03-01 | 2018-09-18 |
| Vorinostat, Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Fludarabine Phosphate, Cyclophosphamide, Rituximab - Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2009-06-01 | 2020-02-25 |
| Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery Dasatinib, Pharmacological Study - Adult Acute Lymphoblastic Leukemia in Remission, Adult B Acute Lymphoblastic Leukemia | Phase 1 | Completed | National Cancer Institute (NCI) | 80 | 2008-10-01 | 2015-07-02 |
| Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma fenretinide, rituximab - Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 32 | 2005-10-01 | 2014-10-06 |
| Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer Fludarabine Phosphate, Total-Body Irradiation, Peripheral Blood Stem Cell Transplantation - Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome | Phase 2 | Completed | Fred Hutchinson Cancer Center | 210 | 2004-11-01 | 2019-10-30 |
Leukemia, Lymphocytic, Chronic, B-Cell (7) · Hodgkin Disease (4) · Lymphoma, B-Cell, Marginal Zone (4) · Lymphoma, Follicular (4) · Lymphoma, Large B-Cell, Diffuse (4) · Lymphoma, Mantle-Cell (4) · Waldenstrom Macroglobulinemia (4) · Burkitt Lymphoma (3) · Lymphoma, Large-Cell, Immunoblastic (3) · Lymphoma, Non-Hodgkin (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Intraocular Lymphoma (2) · Lymphoma, Large-Cell, Anaplastic (2) · Blast Crisis (1) · Carcinoma, Hepatocellular (1)
Chronic Disease (7) · Disease Attributes (7) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Leukemia (7) · Leukemia, B-Cell (7) · Leukemia, Lymphoid (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7)
Cyclophosphamide (4) · Rituximab (4) · fludarabine phosphate (2) · Dasatinib (1) · Doxorubicin (1) · Etoposide (1) · Fenretinide (1) · Lenalidomide (1) · Mycophenolic Acid (1) · Pentostatin (1) · Peripheral Blood Stem Cell Transplantation (1) · Prednisone (1) · Sirolimus (1) · Tacrolimus (1) · Vincristine (1)
National Cancer Institute (NCI) (3) · Fred Hutchinson Cancer Center (2) · Mayo Clinic (1) · University of Chicago (1)
United States (7) · Denmark (1) · Germany (1)
Ajay Gopal (1) · Brenda Sandmaier (1) · John Sarantopoulos (1) · Joseph Flynn (1) · Mazyar Shadman (1) · Sonali Smith (1) · Tait Shanafelt (1)
PMID 24431228, PMID 25085357, PMID 27570087, PMID 32499241, PMID 40720747
P30CA015704 (2), P01CA018029 (1), P30CA014599 (1), P30CA015083 (1), P30CA016058 (1), R21CA119519 (1), U01CA076576 (1), U10CA032102 (1), U10CA180888 (1)