3 completed. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
Follow Smith-Lemli-Opitz Syndrome: new trials by email Literature Review of Smith-Lemli-Opitz Syndrome trials Research Report on Smith-Lemli-Opitz Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smith-Lemli-Opitz Syndrome and Cholic Acid Cholic Acid - Smith-Lemli-Opitz Syndrome | Phase 1 / Phase 2 | Completed | University of Nebraska | 12 | 2021-03-27 | 2024-04-30 |
| Cholesterol in ASD: Characterization and Treatment Cholesterol - Autism, Asperger Disorder | Phase 1 / Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 44 | 2009-07-28 | 2018-07-05 |
| Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome crystalline cholesterol oil-based suspension - Smith-Lemli-Opitz Syndrome | Phase 1 / Phase 2 | Completed | Boston Children's Hospital | 23 | 1998-01-01 | 2017-10-20 |
Asperger Syndrome (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · Child Development Disorders, Pervasive (1) · Congenital Abnormalities (1) · Intellectual Disability (1)
Abnormalities, Multiple (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Dyslipidemias (3) · Genetic Diseases, Inborn (3) · Lipid Metabolism Disorders (3) · Lipid Metabolism, Inborn Errors (3) · Metabolic Diseases (3) · Metabolism, Inborn Errors (3) · Nutritional and Metabolic Diseases (3) · Steroid Metabolism, Inborn Errors (3) · Congenital Abnormalities (2) · Mental Disorders (2) · Neurodevelopmental Disorders (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1)
Cholesterol (1) · Cholic Acid (1)
Boston Children's Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · University of Nebraska (1)
United States (3)
Ellen R Elias, MD (1) · Forbes D Porter, M.D. (1) · Mira Irons, M.D. (1) · William B Rizzo, MD (1)
PMID 14605787, PMID 14662594, PMID 8209913, PMID 9024564, PMID 9024565