5 completed, 1 active not recruiting, 1 terminated. 3 Phase 3, 2 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Not applicable | 1 | Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Cholic Acid: new trials by email Literature Review of Cholic Acid trials Research Report on Cholic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smith-Lemli-Opitz Syndrome and Cholic Acid Cholic Acid - Smith-Lemli-Opitz Syndrome | Phase 1 / Phase 2 | Completed | University of Nebraska | 12 | 2021-03-27 | 2024-04-30 |
| The REPLACE Registry for Cholbam® (Cholic Acid) Cholbam - Bile Acid Synthesis Disorders | Active not recruiting | Mirum Pharmaceuticals, Inc. | 55 | 2017-07-10 | 2026-07-31 | |
| Efficacy of To Be Marketed (TBM) Cholic Acid Capsules Used to Treat Children With Inborn Errors of Bile Acid Synthesis Cholic acid - Inborn Errors of Bile Acid Synthesis | Phase 3 | Completed | Mirum Pharmaceuticals, Inc. | 16 | 2010-04-01 | 2023-10-03 |
| Open Label, Continuation Study of Cholic Acid in Subjects With Inborn Errors of Bile Acid Synthesis Cholic Acid - Bile Acid Synthesis Defect | Phase 3 | Completed | Mirum Pharmaceuticals, Inc. | 53 | 2010-01-01 | 2023-10-03 |
| Cholic Acid for Hepatic Steatosis in Lipodystrophy Cholic Acid - Hepatic Steatosis | Phase 2 | Completed | University of Texas Southwestern Medical Center | 18 | 2006-04-01 | 2025-08-06 |
| Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid Cholic Acids - Infantile Refsum's Disease, Zellweger Syndrome | Phase 3 | Completed | Mirum Pharmaceuticals, Inc. | 85 | 1992-01-01 | 2023-10-03 |
| Study of Bile Acids in Patients With Peroxisomal Disorders chenodeoxycholic acid, cholic acid, ursodiol - Infantile Refsum's Disease, Zellweger Syndrome | Not applicable | Terminated | University of Cincinnati | 25 | 2015-03-25 |
Peroxisomal Disorders (3) · Zellweger Syndrome (3) · Adrenoleukodystrophy (2) · Refsum Disease, Infantile (2) · Cholestasis (1) · Fatty Liver (1) · Lipodystrophy (1) · Liver Diseases (1) · Metabolism, Inborn Errors (1) · Pseudo-Zellweger syndrome (1) · Rare Diseases (1) · Smith-Lemli-Opitz Syndrome (1) · Sphingolipidoses (1)
Mirum Pharmaceuticals, Inc. (4) · University of Cincinnati (1) · University of Nebraska (1) · University of Texas Southwestern Medical Center (1)
United States (6)
James E Heubi, MD (2) · Kenneth Setchell, PhD (2) · Abhimanyu Garg, M.D. (1) · Ellen R Elias, MD (1) · James Heubi, MD (1) · Kenneth Setchell (1) · Sagar A Vaidya, MD, PhD (1) · William B Rizzo, MD (1)