2 active not recruiting. 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 2 |
| Phase 2 | 2 | Active not recruiting 2 |
Follow Sickle Cell Anemia: new trials by email Literature Review of Sickle Cell Anemia trials Research Report on Sickle Cell Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia TBI, Hydroxyurea, briquilimab - Sickle Cell Anemia, Beta Thalassemia | Phase 1 / Phase 2 | Active not recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 40 | 2022-05-12 | 2026-03-12 |
| Haploidentical PBMC Transplant for Severe Congenital Anemias PBSC Transplant, Alemtuzumab, Sirolimus - Sickle Cell Anemia | Phase 1 / Phase 2 | Active not recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 23 | 2009-12-14 | 2026-04-23 |
Anemia, Sickle Cell (2) · Graft vs Host Disease (1) · Thalassemia (1) · beta-Thalassemia (1)
Anemia (2) · Anemia, Hemolytic (2) · Anemia, Hemolytic, Congenital (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Hemoglobinopathies (2) · Immune System Diseases (1) · Thalassemia (1)
Alemtuzumab (2) · Sirolimus (2) · Cyclophosphamide (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Hydroxyurea (1) · Radiation (1) · plerixafor (1)
National Heart, Lung, and Blood Institute (NHLBI) (2)
United States (2)
Courtney D Fitzhugh, M.D. (1) · John F Tisdale, M.D. (1)