3 active not recruiting. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 3 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Sarcoma, Synovial: new trials by email Literature Review of Sarcoma, Synovial trials Research Report on Sarcoma, Synovial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors Letetresgene autoleucel (lete-cel, GSK3377794), Fludarabine, Cyclophosphamide - Neoplasms | Phase 2 | Active not recruiting | USWM CT, LLC | 103 | 2019-12-31 | 2026-08-11 |
| Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma afamitresgene autoleucel (previously ADP-A2M4) - Synovial Sarcoma, Myxoid Liposarcoma | Phase 2 | Active not recruiting | USWM CT, LLC | 52 | 2019-08-13 | 2026-08-26 |
| Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1 Cyclophosphamide, Decitabine, Laboratory Biomarker Analysis - Advanced Fallopian Tube Carcinoma, Advanced Malignant Solid Neoplasm | Phase 1 / Phase 2 | Active not recruiting | Roswell Park Cancer Institute | 15 | 2017-07-14 | 2026-07-08 |
Liposarcoma, Myxoid (2) · Fallopian Tube Neoplasms (1) · Melanoma (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Sarcoma (1)
Neoplasms by Histologic Type (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Liposarcoma (2) · Neoplasms (2) · Neoplasms, Adipose Tissue (2) · Sarcoma (2) · Adnexal Diseases (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1) · Fallopian Tube Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1)
Cyclophosphamide (2) · Decitabine (1) · Injections (1) · Leukapheresis (1) · fludarabine (1)
USWM CT, LLC (2) · Roswell Park Cancer Institute (1)
United States (3) · Canada (2) · France (2) · Spain (2) · United Kingdom (2) · Italy (1) · Netherlands (1)
Dejka Araujo, MD (1) · Michael Nathenson, MD (1) · Philip McCarthy, MD (1)
P30CA016056 (1), R01CA164333 (1)