3 completed, 1 terminated. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Renal Dysfunction: new trials by email Literature Review of Renal Dysfunction trials Research Report on Renal Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction Danicopan - Healthy, Renal Dysfunction | Phase 1 | Completed | Alexion Pharmaceuticals, Inc. | 16 | 2018-01-24 | 2021-06-23 |
| The Effect of Renal Impairment on the Pharmacokinetics of Oral Treprostinil UT-15C SR (treprostinil diethanolamine) - Pulmonary Arterial Hypertension, Renal Dysfunction | Phase 1 | Completed | United Therapeutics | 16 | 2010-05-01 | 2012-05-17 |
| Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction BNP and PDE-V, BNP - Heart Failure, Renal Dysfunction | Phase 1 / Phase 2 | Completed | Mayo Clinic | 60 | 2009-10-01 | 2020-01-18 |
| Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction low dose Nesiritide, nesiritide, Sildenafil - Congestive Heart Failure, Renal Dysfunction | Phase 1 | Terminated | Mayo Clinic | 1 | 2009-02-01 | 2010-09-24 |
Renal Insufficiency (4) · Heart Failure (2) · Pulmonary Arterial Hypertension (1)
Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Kidney Diseases (4) · Male Urogenital Diseases (4) · Urogenital Diseases (4) · Urologic Diseases (4) · Cardiovascular Diseases (2) · Heart Diseases (2) · Hypertension, Pulmonary (1) · Lung Diseases (1) · Respiratory Tract Diseases (1)
Natriuretic Peptide, Brain (2) · Sildenafil Citrate (2) · danicopan (1) · rhoA GTP-Binding Protein (1) · treprostinil (1)
Mayo Clinic (2) · Alexion Pharmaceuticals, Inc. (1) · United Therapeutics (1)
United States (3)
Dr Horng H Chen, MD (1) · Horng H Chen, MD (1) · Thomas Marbury, MD (1)