23 completed, 4 terminated. 13 Phase 1, 13 Phase 2, 4 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 9, Terminated 4 |
| Phase 2 | 13 | Completed 12, Terminated 1 |
| Not applicable | 4 | Completed 4 |
| Early Phase 1 | 1 | Completed 1 |
Follow Recurrent Childhood Anaplastic Large Cell Lymphoma: new trials by email Literature Review of Recurrent Childhood Anaplastic Large Cell Lymphoma trials Research Report on Recurrent Childhood Anaplastic Large Cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant busulfan, etoposide, cyclophosphamide - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 33 | 2014-03-01 | 2015-08-13 |
| MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma anti-endosialin/TEM1 monoclonal antibody MORAb-004, pharmacological study, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 | Completed | Morphotek | 27 | 2013-11-01 | 2016-01-08 |
| Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma Crizotinib, Cyclophosphamide, Dexrazoxane Hydrochloride - Childhood Solid Neoplasm, Recurrent Childhood Anaplastic Large Cell Lymphoma | Phase 1 | Completed | Children's Oncology Group | 46 | 2013-04-29 | 2024-01-05 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia Akt inhibitor MK2206, diagnostic laboratory biomarker analysis, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Acute Leukemias of Ambiguous Lineage | Phase 1 | Completed | National Cancer Institute (NCI) | 45 | 2011-01-01 | 2014-04-29 |
| Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer massage therapy, questionnaire administration, quality-of-life assessment - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Wake Forest University Health Sciences | 80 | 2010-04-01 | 2018-07-02 |
| Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia gamma-secretase/Notch signalling pathway inhibitor RO4929097, diagnostic laboratory biomarker analysis, pharmacological study - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 129 | 2010-03-01 | 2014-11-05 |
| Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma Crizotinib, Laboratory Biomarker Analysis, Pharmacological Study - Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Malignant Solid Neoplasm | Phase 1 / Phase 2 | Completed | Children's Oncology Group | 122 | 2009-09-21 | 2020-06-09 |
| Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma vorinostat, bortezomib, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-08-01 | 2013-07-02 |
| Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia dexrazoxane hydrochloride, doxorubicin hydrochloride, obatoclax mesylate - Acute Leukemias of Ambiguous Lineage, Acute Undifferentiated Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 22 | 2009-06-01 | 2014-05-01 |
| Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Not applicable | Completed | Roswell Park Cancer Institute | 62 | 2009-01-14 | 2019-11-13 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma bevacizumab, cediranib maleate - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 | Completed | National Cancer Institute (NCI) | 57 | 2007-05-01 | 2014-02-19 |
| Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma monoclonal antibody SGN-30, therapeutic hydrocortisone, ifosfamide - Anaplastic Large Cell Lymphoma, Recurrent Childhood Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 5 | 2007-01-01 | 2018-03-14 |
| High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors etoposide, cyclophosphamide, carmustine - Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission | Not applicable | Completed | Roswell Park Cancer Institute | 174 | 2006-06-29 | 2021-04-22 |
| A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies cyclophosphamide, fludarabine phosphate, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | Fred Hutchinson Cancer Center | 23 | 2006-04-01 | 2015-02-11 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma oxaliplatin, etoposide - Angioimmunoblastic T-cell Lymphoma, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 40 | 2004-11-01 | 2014-02-24 |
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Lymphoma, Large-Cell, Anaplastic (27) · Burkitt Lymphoma (24) · Dendritic Cell Sarcoma, Interdigitating (24) · Lymphoma, Large B-Cell, Diffuse (23) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (23) · Lymphoma, Extranodal NK-T-Cell (22) · Leukemia, Lymphocytic, Chronic, B-Cell (21) · Recurrence (21) · Lymphoma, B-Cell, Marginal Zone (19) · Lymphoma, Follicular (19) · Lymphoma, Mantle-Cell (19) · Mycosis Fungoides (19) · Sezary Syndrome (19) · Lymphoma, Large-Cell, Immunoblastic (18) · Lymphoma, Non-Hodgkin (18)
Hemic and Lymphatic Diseases (27) · Immune System Diseases (27) · Immunoproliferative Disorders (27) · Lymphatic Diseases (27) · Lymphoma (27) · Lymphoma, T-Cell (27) · Lymphoproliferative Disorders (27) · Neoplasms (27) · Neoplasms by Histologic Type (27) · DNA Virus Infections (24) · Disease Attributes (24) · Epstein-Barr Virus Infections (24) · Herpesviridae Infections (24) · Histiocytic Disorders, Malignant (24) · Histiocytosis (24)
Whole-Body Irradiation (12) · fludarabine phosphate (12) · Mycophenolic Acid (11) · Peripheral Blood Stem Cell Transplantation (10) · Cyclosporine (8) · Cyclophosphamide (7) · Busulfan (4) · Etoposide (4) · Tacrolimus (4) · Melphalan (3) · Alemtuzumab (2) · Antilymphocyte Serum (2) · Carboplatin (2) · Crizotinib (2) · Dexrazoxane (2)
Fred Hutchinson Cancer Center (10) · National Cancer Institute (NCI) (7) · Roswell Park Cancer Institute (3) · Case Comprehensive Cancer Center (2) · Children's Oncology Group (2) · Morphotek (1) · University of Chicago (1) · Wake Forest University Health Sciences (1)
United States (27) · Italy (6) · Canada (5) · Germany (3) · Denmark (1)
Brenda Sandmaier (4) · David Maloney (3) · George Chen (2) · Brenda Cooper, MD (1) · Brian Hill, MD (1) · Colleen Delaney (1) · David Hong (1) · Emily Greengard (1) · Hongtao Liu (1) · Janet Tooze, PhD (1) · Jodi Muscal (1) · John Sandlund (1) · Lisa McGregor (1) · Marco Mielcarek (1) · Maryam Fouladi (1)
PMID 32499241, PMID 41920422, PMID 19900571, PMID 23393050, PMID 23598171, PMID 25085357, PMID 26764356, PMID 28032129, PMID 29292843, PMID 33095287, PMID 33568345
P30CA015704 (8), U01CA097452 (5), P01CA018029 (4), P01CA078902 (2), UM1CA097452 (2), P30CA016056 (1), P30CA016672 (1), P30CA021765 (1), P30CA043703 (1), R24HL074445 (1), R43HL106868 (1), RC2HL101844 (1), U01CA062461 (1), U10CA098543 (1)