2 not yet recruiting, 1 active not recruiting, 1 recruiting, 1 terminated. 2 Phase 2, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Active not recruiting 1, Terminated 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Prosthetic Joint Infections of Knee: new trials by email Literature Review of Prosthetic Joint Infections of Knee trials Research Report on Prosthetic Joint Infections of Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| oneKNEE - Prospective, Non-interventional, Multicenter PMCF-Study oneKNEE® - Arthroplasty, Arthroplasty Replacement, Knee | Not yet recruiting | Aesculap AG | 1020 | 2027-04-01 | 2026-08-14 | |
| Antibiotic-coated Braided Suture Study VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament - Prosthetic Joint Infection, Debridement With Prosthesis Retention | Not applicable | Not yet recruiting | University of Miami | 142 | 2026-11-01 | 2026-07-08 |
| Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection TRL1068 (calpurbatug), a human monoclonal antibody, DAIR - Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee | Phase 2 | Active not recruiting | Trellis Bioscience LLC | 60 | 2025-04-08 | 2026-05-07 |
| ROADMAP Clinical Trial Debridement and Implant Retention (DAIR), Antibiotic Choice, Antibiotic duration Part A - Single stage revision - Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee | Phase 4 | Recruiting | University of Newcastle, Australia | 2500 | 2025-03-24 | 2026-07-27 |
| Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection CEM-102, IV or Oral standard of care antibiotics, Rifampin - Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee | Phase 2 | Terminated | Arrevus Inc. | 14 | 2012-12-01 | 2019-04-19 |
Debridement (2) · Anti-Bacterial Agents (1) · Cefazolin (1) · Ceftaroline (1) · Ceftriaxone (1) · Ciprofloxacin (1) · Daptomycin (1) · Fusidic Acid (1) · Levofloxacin (1) · Linezolid (1) · Nafcillin (1) · Oxacillin (1) · Rifampin (1) · TRL1068 (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1)
Aesculap AG (1) · Arrevus Inc. (1) · Trellis Bioscience LLC (1) · University of Miami (1) · University of Newcastle, Australia (1)
United States (3) · Australia (1) · New Zealand (1)
Anne Postler, PD Dr. med (1) · Colin McNamara, MD (1) · Laurens Manning, Co-chief Investigator, infectious diseases Specialist (1)