2 completed, 1 active not recruiting, 1 not yet recruiting, 1 unknown. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate Safety and Activity of Inhaled TRL1068 in Healthy Volunteers TRL1068, a human monoclonal antibody - Healthy Volunteer | Phase 1 | Not yet recruiting | Trellis Bioscience LLC | 14 | 2026-10-01 | 2026-06-12 |
| Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection TRL1068 (calpurbatug), a human monoclonal antibody, DAIR - Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee | Phase 2 | Active not recruiting | Trellis Bioscience LLC | 60 | 2025-04-08 | 2026-05-07 |
| Study to Evaluate Safety and Activity of TRL1068 in Chronic Rhinosinusitis TRL1068 - Chronic Rhinosinusitis With Nasal Polyps | Phase 1 | Unknown | Trellis Bioscience LLC | 12 | 2024-01-01 | 2023-04-12 |
| Study to Evaluate Safety and Activity of TRL345 in Healthy Volunteers TRL345, a human monoclonal antibody - Healthy Volunteers | Phase 1 | Completed | Trellis Bioscience LLC | 16 | 2023-09-14 | 2026-06-25 |
| Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections TRL1068, a human monoclonal antibody - Prosthetic Joint Infection | Phase 1 | Completed | Trellis Bioscience LLC | 15 | 2021-02-08 | 2024-11-21 |
TRL1068 (4) · Anti-Bacterial Agents (1) · Debridement (1)
United States (4)
Daniel Oakes, MD (1) · Edward Stolarski, MD (1) · Ian Duensing, MD (1) · Janet Conway, MD (1) · Luis Pulido, MD (1) · Nicholas Bernthal, MD (1) · Richard Berkowitz, MD (1) · Sameer Naranje, MD (1) · Stephen Incavo, MD (1)