2 completed, 1 terminated, 1 unknown. 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Prophylaxis: new trials by email Literature Review of Prophylaxis trials Research Report on Prophylaxis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Protect: Study With Hydroxychloroquine for Prevention and Early Phase Treatment of Coronavirus Disease (COVID-19) Hydroxychloroquine - COVID19, Hydroxychloroquine | Phase 2 | Terminated | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | 155 | 2020-05-14 | 2025-03-10 |
| Ciprofloxacin Versus Levofloxacin in Stem Cell Transplant Levofloxacin, Ciprofloxacin - Prophylaxis, Stem Cell Transplant Complications | Phase 2 | Completed | Henry Ford Health System | 308 | 2018-03-14 | 2025-10-20 |
| A Long Term Safety Study of BCX7353 in Hereditary Angioedema BCX7353 - Hereditary Angioedema, HAE | Phase 2 / Phase 3 | Completed | BioCryst Pharmaceuticals | 387 | 2018-02-16 | 2023-06-18 |
| Low Dose ATG Plus Low Dose PTCy as GVHD Prophylaxis in Haplo-HSCT ATG - Graft-versus-host-disease, Prophylaxis | Phase 2 | Unknown | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 100 | 2017-05-30 | 2019-04-16 |
Angioedemas, Hereditary (1) · COVID-19 (1) · Graft vs Host Disease (1)
Immune System Diseases (2) · Angioedema (1) · Cardiovascular Diseases (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Genetic Diseases, Inborn (1) · Hereditary Complement Deficiency Diseases (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Immunologic Deficiency Syndromes (1) · Infections (1) · Lung Diseases (1) · Nidovirales Infections (1) · Pneumonia (1)
Ciprofloxacin (1) · Hydroxychloroquine (1) · Levofloxacin (1) · berotralstat (1)
BioCryst Pharmaceuticals (1) · Henry Ford Health System (1) · Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS (1) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (1)
Italy (2) · United States (2) · Australia (1) · Austria (1) · China (1) · Denmark (1) · France (1) · Germany (1) · Hong Kong (1) · Hungary (1) · Israel (1) · New Zealand (1) · North Macedonia (1) · Poland (1) · Serbia (1)
Giovanni Martinelli, Prof. (1) · Henriette Farkas, MD (1) · Pierluigi Viale, Prof. (1)
PMID 32736597, PMID 34161665, PMID 35820771, PMID 36408587, PMID 38006972, PMID 38020288, PMID 39019103, PMID 40490218