4 recruiting. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 3 |
| Phase 1 | 1 | Recruiting 1 |
Follow Primary Immune Regulatory Disorder: new trials by email Literature Review of Primary Immune Regulatory Disorder trials Research Report on Primary Immune Regulatory Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD) Hematopoietic stem cell transplant (HSCT) - Common Variable Immunodeficiency (CVID), Primary Immune Regulatory Disorder | Phase 2 | Recruiting | Paul Szabolcs | 25 | 2026-05-04 | 2026-05-15 |
| Enhancing the Clinical Management of CMF Through a National Pediatric and Adult Network Based on Biological and Genetic Data Inherited Bone Marrow Failure Syndrome, Fanconi Anemia | Recruiting | Istituto Giannina Gaslini | 250 | 2025-05-29 | 2026-10-16 | |
| Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT Phase 1 Dose Level 1, Phase 1 Dose Level 2, Phase 1 Dose Level 3 - Leukemia, High Risk Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Recruiting | Children's Hospital of Philadelphia | 100 | 2025-03-21 | 2026-04-15 |
| A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition Emapalumab, Fludarabine and Dexamethasone, Allogeneic hematopoietic stem cell transplant (allo-HCT) - Primary Immune Regulatory Disorder, Autoimmune Lymphoproliferative | Phase 2 | Recruiting | Joseph Oved | 39 | 2023-03-15 | 2026-06-02 |
Congenital Bone Marrow Failure Syndromes (2) · Anemia, Refractory, with Excess of Blasts (1) · Bone Marrow Failure Disorders (1) · Common Variable Immunodeficiency (1) · Congenital amegakaryocytic thrombocytopenia (1) · DiGeorge Syndrome (1) · Dyskeratosis Congenita (1) · Fanconi Anemia (1) · Granulomatous Disease, Chronic (1) · Hemoglobinopathies (1) · Hemoglobinuria, Paroxysmal (1) · Hyper-IgM Immunodeficiency Syndrome (1) · Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Infant, Newborn, Diseases (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Anemia (2) · Bone Marrow Diseases (2) · Congenital Abnormalities (2) · DNA Repair-Deficiency Disorders (2) · Genetic Diseases, X-Linked (2) · Immune System Diseases (2) · Lymphatic Diseases (2) · Myelodysplastic Syndromes (2)
Stem Cell Transplantation (2) · Clinical Trials, Phase I as Topic (1) · Dexamethasone (1) · Emapalumab (1) · fludarabine (1)
Children's Hospital of Philadelphia (1) · Istituto Giannina Gaslini (1) · Joseph Oved (1) · Paul Szabolcs (1)
United States (3) · Italy (1)
Joseph Oved, MD (1) · Paul Szabolcs, MD (1) · Timothy Olson, MD, PhD (1)