6 completed. 6 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Plasmodium Falciparum: new trials by email Literature Review of Plasmodium Falciparum trials Research Report on Plasmodium Falciparum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial Therapy Malaria Vaccine RTS,S/AS01E, Abhayrab rabies vaccine, Dihydroartemisinin-piperaquine (DHA/Pip) - Plasmodium Falciparum | Phase 2 | Completed | PATH | 620 | 2020-11-06 | 2024-07-19 |
| Safety and Protective Efficacy of Pb(PfCS@UIS4) Pb(PfCS@UIS4)-infected mosquitoes, Challenge infection P. falciparum - Malaria,Falciparum, Plasmodium Falciparum | Phase 1 / Phase 2 | Completed | Radboud University Medical Center | 24 | 2017-05-29 | 2022-03-04 |
| Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection BCG vaccination - Malaria, Plasmodium Falciparum | Phase 2 | Completed | Radboud University Medical Center | 20 | 2016-04-01 | 2017-04-20 |
| Low Dose Primaquine for Clearance of Gametocytes Artemether-lumefantrine combination, Artemether-Lumefantrine with a single dose of 0.25mg/kg primaquine, Artemether-Lumefantrine with a single dose of 0.4mg/kg primaquine - Malaria, Asymptomatic Malaria | Phase 2 / Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 360 | 2013-09-01 | 2015-09-02 |
| NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1 NMRC-M3V-Ad-PfCA, NMRC-MV-Ad-PfC, NMRC-M3V-Ad-PfCA - Plasmodium Falciparum | Phase 1 / Phase 2 | Completed | U.S. Army Medical Research and Development Command | 59 | 2006-10-12 | 2021-05-21 |
| Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults. RTS, S/AS01B, RTS, S/AS02A, Rabipur (Rabies) Vaccine - Plasmodium Falciparum | Phase 2 | Completed | U.S. Army Medical Research and Development Command | 255 | 2005-07-01 | 2021-02-12 |
Malaria, Falciparum (6) · Malaria (2) · Adenoviridae Infections (1)
Infections (6) · Mosquito-Borne Diseases (6) · Parasitic Diseases (6) · Protozoan Infections (6) · Vector Borne Diseases (6) · Malaria (4) · DNA Virus Infections (1) · Virus Diseases (1)
Artemether, Lumefantrine Drug Combination (2) · Primaquine (2) · RTS malaria vaccine (1) · RTS,S-AS01B vaccine (1) · RTS,S-AS02A vaccine (1) · Vaccines (1)
Radboud University Medical Center (2) · U.S. Army Medical Research and Development Command (2) · London School of Hygiene and Tropical Medicine (1) · PATH (1)
Kenya (2) · Netherlands (2) · Burkina Faso (1) · United States (1)
Alfred Tiono, PhD, MD (1) · Cindy Tamminga, MD, MPH (1) · Jona Walk, MD (1) · Lucas O Tina, MD, MTM&H (1) · Mihai Netea, Prof. (1) · Robert Sauerwein, MD PhD (1) · Robert Sauerwein, Prof. (1)
PMID 19649245, PMID 22003383, PMID 22003411, PMID 23899517, PMID 25211344, PMID 26292027, PMID 26292257, PMID 26952094, PMID 27695088, PMID 28289025, PMID 32434846, PMID 40439411
2015 (1)