8 completed, 4 unknown, 3 active not recruiting, 3 recruiting. 12 Not applicable, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 4, Recruiting 3, Unknown 3, Active not recruiting 1, Withdrawn 1 |
| Phase 4 | 2 | Active not recruiting 2 |
| Phase 2 | 1 | Completed 1 |
Follow Peyronie Disease: new trials by email Literature Review of Peyronie Disease trials Research Report on Peyronie Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Extracorporeal Shockwave Therapy in the Treatment of Peyronie's Disease Extracorporeal Shockwave Therapy, control - Peyronie Disease | Not applicable | Recruiting | Uskudar University | 50 | 2026-01-10 | 2026-01-16 |
| Platelet-Rich Plasma Injections From Cord Blood + Penile Traction vs. Penile Traction Alone in Patients With Peyronie's Disease. Open-label, Single-center Randomized Study Injection - Peyronie Disease, Penile Curvature | Not applicable | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 42 | 2025-05-28 | 2025-06-08 |
| Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease Collagenase Clostridium Histolyticum, RestoreX, Sildenafil - Peyronie Disease | Phase 4 | Active not recruiting | Charitable Union for the Research and Education of Peyronie's Disease | 40 | 2024-10-11 | 2026-08-26 |
| Peyronie Disease Questionnaire (PDQ): Turkish Validation Peyronie Disease | Unknown | Acibadem University | 60 | 2024-09-01 | 2024-10-01 | |
| Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease Collagenase Clostridium Histolyticum, Storz Duolith LiSWT - Peyronie Disease, Erectile Dysfunction | Not applicable | Recruiting | Mayo Clinic | 60 | 2024-01-19 | 2026-10-16 |
| Non-ablative Radiofrequency and Low Intensity Shock Wave Therapy in Fibrotic Plaque in Men With Peyronie's Disease Non-ablative Radiofrequency, Low-intensity Shock Wave Therapy - Peyronie Disease | Not applicable | Unknown | Centro de Atenção ao Assoalho Pélvico | 10 | 2024-01-08 | 2024-05-29 |
| Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease Collagenase Clostridium Histolyticum (CCH) - Peyronie Disease, Sexual Dysfunctions, Psychological | Phase 4 | Active not recruiting | University of Miami | 12 | 2023-10-02 | 2026-06-04 |
| Pilot Study on the Efficacy and Safety of FIBRORESTIL® as an Adjuvant Intralesional Treatment in Patients With Peyronie's Disease Receiving Standard Therapy Intralesional hyaluronic acid-based enzymatic medical device, Standard conservative treatment for Peyronie's disease - Peyronie Disease | Not applicable | Active not recruiting | Lyx Institute | 38 | 2023-06-15 | 2026-01-14 |
| Safety and Efficacy of Intralesional HiLow Hyaluronic Acid in the Treatment of Peyronie's Disease (PD) Pre-filled syringe of HiLow Hyaluronic Acid Sodium Salt - Peyronie Disease | Not applicable | Completed | IBSA Farmaceutici Italia Srl | 40 | 2023-05-21 | 2025-01-08 |
| French Translation and Validation of the PEYronie's Disease QUESTionnaire FRAnçaise du PEYronie's Disease QUESTionnaire - Peyronie Disease | Completed | University Hospital, Toulouse | 30 | 2023-03-06 | 2024-08-27 | |
| Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction Collagenase Clostridium Histolyticum, Duolith SD1 T-TOP - Peyronie Disease, Penile Curvature | Not applicable | Withdrawn | Mayo Clinic | 2023-03-01 | 2023-10-10 | |
| Pelvic CT with Agatston Calcium Score for Peyronie Disease CT exam - Peyronie Disease | Not applicable | Completed | Mayo Clinic | 12 | 2022-08-04 | 2024-09-19 |
| Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease Low intensity choc waves therapy (active applicator), Sham (sham applicator) - Peyronie Disease, Penile Diseases | Not applicable | Completed | Hopital Foch | 120 | 2021-04-06 | 2024-07-31 |
| PRP for Treatment of Peyronie's Disease Autologous Platelet-Rich Plasma (PRP), Placebo (Normal Saline) - Peyronie Disease, Sexual Dysfunction, Physiological | Phase 2 | Completed | University of Miami | 65 | 2021-03-29 | 2026-08-03 |
| Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment Nanofat grafing - Peyronie Disease | Not applicable | Unknown | University of Roma La Sapienza | 35 | 2021-01-01 | 2022-07-08 |
| Treatment Response to Xiaflex for Men With Peyronie's Disease Peyronie Disease | Completed | University of Miami | 80 | 2018-09-02 | 2021-09-29 | |
| Low-Intensity Extracorporeal Shockwave Therapy and Vacuum Erectile Device as a Treatment for Peyronies Disease. low-intensity extracorporeal shockwave therapy, Placebo LI-ESWT, Penile pump - Peyronie Disease | Not applicable | Unknown | Odense University Hospital | 50 | 2018-03-13 | 2019-03-14 |
| Does Size Matter: A Single Case Experimental Design of Limiting the Depth of Penetration During Intercourse Penile Ring - Peyronie Disease | Not applicable | Completed | King's College London | 12 | 2017-03-01 | 2019-08-09 |
| Medical Treatment of Peyronie's Disease With Collagenase Clostridium Histolyticum Peyronie Disease | Completed | University Hospital, Montpellier | 156 | 2015-01-01 | 2020-05-01 |
Penile Induration (19) · Erectile Dysfunction (2) · Genital Diseases, Male (2) · Sexual Dysfunction, Physiological (2) · Insomnia, Fatal Familial (1) · Penile Diseases (1) · Sexual Dysfunctions, Psychological (1)
Connective Tissue Diseases (19) · Genital Diseases (19) · Male Urogenital Diseases (19) · Skin and Connective Tissue Diseases (19) · Urogenital Diseases (19) · Penile Diseases (18) · Genital Diseases, Male (17) · Mental Disorders (3) · Sexual Dysfunction, Physiological (2) · Sexual Dysfunctions, Psychological (2) · Central Nervous System Diseases (1) · Central Nervous System Infections (1) · Dyssomnias (1) · Infections (1) · Nervous System Diseases (1)
Microbial Collagenase (4) · Extracorporeal Shockwave Therapy (1) · Injections (1) · Saline Solution (1) · Sildenafil Citrate (1)
Mayo Clinic (3) · University of Miami (3) · Acibadem University (1) · Centro de Atenção ao Assoalho Pélvico (1) · Charitable Union for the Research and Education of Peyronie's Disease (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Hopital Foch (1) · IBSA Farmaceutici Italia Srl (1) · King's College London (1) · Lyx Institute (1) · Odense University Hospital (1) · University Hospital, Montpellier (1) · University Hospital, Toulouse (1) · University of Roma La Sapienza (1) · Uskudar University (1)
United States (7) · France (3) · Italy (3) · Azerbaijan (1) · Brazil (1) · Denmark (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Aziz Azizov (1) · Edouard Fortier, MD (1) · Eric Huyghe, MD (1) · Franco Gadda, MD (1) · Landon Trost, MD (1) · Lauren Alexander, MD (1) · Manuel Molina, MD (1) · Ranjith Ramasamy, MD (1) · Thomas Masterson, MD (1) · Tobias Kohler, MD (1) · Tobias Kohler, MD, MPH (1)
PMID 16921694, PMID 17983892, PMID 18638001, PMID 2231932, PMID 23230545, PMID 23376148, PMID 23421851, PMID 23783059, PMID 25711400, PMID 27298777, PMID 34823053, PMID 36100520, PMID 38106680, PMID 42684278, PMID 42704279