2 recruiting, 1 active not recruiting, 1 terminated, 1 unknown. 3 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Neuromyelitis Optica Spectrum Disorder Attack: new trials by email Literature Review of Neuromyelitis Optica Spectrum Disorder Attack trials Research Report on Neuromyelitis Optica Spectrum Disorder Attack
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy Study of Sivelestat in Neuromyelitis Optica Spectrum Disorder Sivelestat sodium hydrate - Neuromyelitis Optica Spectrum Disorder Attack | Phase 1 / Phase 2 | Recruiting | Kyushu University | 7 | 2026-10-01 | 2026-10-07 |
| Therapy in the Acute Phase of NMOSD: A Multicenter Prospective Real-World Study Eculizumab+IVMP, IVIG+IVMP, IVMP - Neuromyelitis Optica Spectrum Disorder Attack | Phase 4 | Recruiting | Chinese PLA General Hospital | 200 | 2026-02-01 | 2026-03-12 |
| Eculizumab For the Acute Attack of Neuromyelitis Optica Spectrum Disorder Intravenous Methylprednisolone (IVMP), Complement protein C5 inhibitor - Neuromyelitis Optica Spectrum Disorder Attack | Phase 2 | Active not recruiting | Tianjin Medical University General Hospital | 110 | 2025-09-09 | 2026-06-03 |
| Eculizumab For Acute Attack of Neuromyelitis Optica Spectrum Disorder Complement protein C5 inhibitor, IVMP - Neuromyelitis Optica Spectrum Disorder Attack | Phase 2 | Withdrawn | Tianjin Medical University General Hospital | 2025-09-03 | 2025-09-10 | |
| Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve non-interventional study - Demyelinating Diseases, Multiple Sclerosis | Unknown | Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecul | 200 | 2020-08-15 | 2022-11-04 | |
| Diagnosis of ON With or Without MS or NMOSD Reflex (Brightlamp Inc., Purdue University) - Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder Attack | Terminated | Jagannadha R Avasarala | 112 | 2019-10-04 | 2022-11-14 |
Neuromyelitis Optica (4) · Multiple Sclerosis (2) · Optic Neuritis (2) · Demyelinating Diseases (1) · Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (1)
Autoimmune Diseases (5) · Autoimmune Diseases of the Nervous System (5) · Cranial Nerve Diseases (5) · Demyelinating Autoimmune Diseases, CNS (5) · Eye Diseases (5) · Immune System Diseases (5) · Nervous System Diseases (5) · Optic Nerve Diseases (5) · Demyelinating Diseases (4) · Myelitis, Transverse (4) · Optic Neuritis (3)
eculizumab (2) · Methylprednisolone (1) · Prednisolone (1) · Reflex (1)
Tianjin Medical University General Hospital (2) · Chinese PLA General Hospital (1) · Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecul (1) · Jagannadha R Avasarala (1) · Kyushu University (1)
China (2) · Japan (2) · United States (2) · Argentina (1) · Australia (1) · Botswana (1) · Brazil (1) · Colombia (1) · Denmark (1) · France (1) · Germany (1) · India (1) · Israel (1) · Italy (1) · South Korea (1)
Hadas Stiebel-Kalish (1) · Jagannadha Avasarala, MD PhD (1) · Susanna Asseyer (1)