4 completed. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 2 | Completed 2 |
Follow Netherton Syndrome: new trials by email Literature Review of Netherton Syndrome trials Research Report on Netherton Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome SXR1096 cream, Placebo cream - Netherton Syndrome | Phase 1 / Phase 2 | Completed | Sixera Pharma | 9 | 2021-12-07 | 2025-12-16 |
| The Efficacy and Safety of Secukinumab in Patients With Ichthyoses Secukinumab, Placebo - Ichthyosis, Autosomal Recessive Congenital Ichthyosis | Phase 2 | Completed | Northwestern University | 20 | 2016-12-01 | 2021-08-25 |
| Clinical Trial Using Humira in Netherton Syndrome Adalimumab - Netherton Syndrome | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 11 | 2014-01-27 | 2026-04-08 |
| Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome Pimecrolimus 1% Cream - Netherton Syndrome | Phase 1 / Phase 2 | Completed | Children's Hospital of Philadelphia | 3 | 2005-09-01 | 2019-08-14 |
Hyperkeratosis, Epidermolytic (1) · Ichthyosiform Erythroderma, Congenital (1) · Ichthyosis (1) · Ichthyosis, Lamellar (1)
Abnormalities, Multiple (4) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Infant, Newborn, Diseases (4) · Keratosis (4) · Skin Abnormalities (4) · Skin Diseases (4) · Skin Diseases, Genetic (4) · Skin and Connective Tissue Diseases (4) · Ichthyosiform Erythroderma, Congenital (3) · Ichthyosis (3)
Adalimumab (1) · WAS protein, human (1) · pimecrolimus (1) · secukinumab (1)
Assistance Publique - Hôpitaux de Paris (1) · Children's Hospital of Philadelphia (1) · Northwestern University (1) · Sixera Pharma (1)
France (2) · United States (2) · Austria (1) · Germany (1) · Sweden (1)
Albert C Yan, MD (1) · Amy Paller, MD (1) · Christine Bodemer, MD, PhD (1) · Emma Guttman-Yassky, MD, PhD (1) · Maarten de Chateau, MD PhD (1)