3 completed, 1 not yet recruiting. 2 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Hyperkeratosis, Epidermolytic: new trials by email Literature Review of Hyperkeratosis, Epidermolytic trials Research Report on Hyperkeratosis, Epidermolytic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidermal Growth Factor Receptor Inhibition for Keratinopathies Erlotinib - Epidermolytic Ichthyosis, Palmoplantar Keratoderma | Phase 1 / Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-07-01 | 2026-08-03 |
| Study of in Vivo and in Vitro Transcriptomic and Proteomic Signatures in Unhereditary Ichtyosis Biological samples, Skin biopsy - Autosomal Recessive Congenital Ichthyosis, Epidermolytic Ichthyosis | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 18 | 2022-12-07 | 2024-07-16 |
| The Efficacy and Safety of Secukinumab in Patients With Ichthyoses Secukinumab, Placebo - Ichthyosis, Autosomal Recessive Congenital Ichthyosis | Phase 2 | Completed | Northwestern University | 20 | 2016-12-01 | 2021-08-25 |
| National Registry for Ichthyosis and Related Disorders Darier Disease, Hailey-Hailey Disease | Completed | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 610 | 1994-09-01 | 2022-09-28 |
Ichthyosiform Erythroderma, Congenital (2) · Ichthyosis (2) · Ichthyosis, Lamellar (2) · Darier Disease (1) · Dermatitis, Exfoliative (1) · Epidermal Nevus (1) · Ichthyosis, X-Linked (1) · Keratoderma, Palmoplantar (1) · Keratosis (1) · Nails, Malformed (1) · Netherton Syndrome (1) · Pachyonychia Congenita (1) · Pemphigus, Benign Familial (1)
Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Infant, Newborn, Diseases (4) · Skin Abnormalities (4) · Skin Diseases (4) · Skin Diseases, Genetic (4) · Skin and Connective Tissue Diseases (4) · Keratosis (3) · Abnormalities, Multiple (2) · Ichthyosiform Erythroderma, Congenital (2) · Ichthyosis (2) · Dermatitis (1) · Ectodermal Dysplasia (1) · Genetic Diseases, X-Linked (1)
Erlotinib Hydrochloride (1) · secukinumab (1)
Northwestern University (2) · Assistance Publique - Hôpitaux de Paris (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1)
United States (3) · France (1)
Amy Paller (1) · Amy Paller, MD (1) · Emma Guttman-Yassky, MD, PhD (1) · Philip Fleckman, MD (1)
PMID 11511292, PMID 11912510, PMID 12648223, PMID 14734878, PMID 15238912, PMID 16250204, PMID 18571597, PMID 18948357, PMID 19241467, PMID 35218370, PMID 9804339, PMID 9843209