2 completed, 1 recruiting, 1 terminated, 1 unknown. 1 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Mevalonate Kinase Deficiency: new trials by email Literature Review of Mevalonate Kinase Deficiency trials Research Report on Mevalonate Kinase Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ilaris NIS in Korea Ilaris - Hereditary Periodic Fever Syndromes, Cryopyrin-associated Periodic Syndromes (CAPS) | Recruiting | Novartis Pharmaceuticals | 25 | 2025-03-29 | 2026-05-19 | |
| Geranylgeraniol Supplementation in Patients With Mevalonate Kinase Deficiency geranylgeraniol - Mevalonate Kinase Deficiency | Not applicable | Unknown | University Hospital, Motol | 6 | 2022-01-25 | 2024-07-12 |
| A Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 Studies canakinumab - Systemic Juvenile Idiopathic Arthritis, Hereditary Periodic Fevers | Phase 3 | Completed | Novartis Pharmaceuticals | 31 | 2014-11-03 | 2020-05-19 |
| B7 Coreceptor Molecules in Hyper IgD Syndrome Form of Mevalonate Kinase Deficiency Hyper IgD Syndrome, Mevalonate Kinase Deficiency | Withdrawn | Michigan Technological University | 2012-03-01 | 2018-06-18 | ||
| Canakinumab in Patients With Active Hyper-IgD Syndrome Canakinumab - Mevalonate Kinase Deficiency | Phase 2 | Completed | Novartis Pharmaceuticals | 9 | 2011-03-01 | 2015-11-05 |
| Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency Mevalonic Aciduria, Mevalonate Kinase Deficiency | Terminated | Oregon Health and Science University | 1 | 2005-02-01 | 2019-05-24 |
Arthritis, Juvenile (2) · Cryopyrin-Associated Periodic Syndromes (2) · Hereditary Autoinflammatory Diseases (2) · Arthralgia (1) · Bronchiolitis Obliterans Syndrome (1) · Fever (1) · Immune System Diseases (1) · Lipid Metabolism, Inborn Errors (1) · Periodic fever, familial, autosomal dominant (1) · Rheumatoid Arthritis, Systemic Juvenile (1)
Blood Protein Disorders (6) · Brain Diseases (6) · Brain Diseases, Metabolic (6) · Brain Diseases, Metabolic, Inborn (6) · Central Nervous System Diseases (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Hypergammaglobulinemia (6) · Immunoproliferative Disorders (6) · Metabolic Diseases (6) · Metabolism, Inborn Errors (6) · Nervous System Diseases (6) · Nutritional and Metabolic Diseases (6)
canakinumab (3) · geranylgeraniol (1)
Novartis Pharmaceuticals (3) · Michigan Technological University (1) · Oregon Health and Science University (1) · University Hospital, Motol (1)
United States (2) · Czechia (1) · France (1) · Netherlands (1) · South Korea (1) · Spain (1)
2014 (1)