22 completed, 18 active not recruiting, 18 terminated, 13 recruiting. 39 Phase 2, 24 Phase 1, 8 Not applicable, 3 Phase 3, 2 Early Phase 1.
Follow Metastatic Prostate Carcinoma: new trials by email Literature Review of Metastatic Prostate Carcinoma trials Research Report on Metastatic Prostate Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer Cancer Therapeutic Procedure, Health Care Delivery, Questionnaire Administration - Biochemically Recurrent Prostate Carcinoma, Locally Advanced Prostate Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 38 | 2025-08-27 | 2026-03-25 |
| Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation Patient Navigation, Genetic Counseling, Survey Administration - Metastatic Prostate Carcinoma, Stage III Prostate Cancer AJCC v8 | Not applicable | Recruiting | Thomas Jefferson University | 120 | 2025-01-01 | 2026-10-22 |
| Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Biopsy, Bone Scan, Computed Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Active not recruiting | Roswell Park Cancer Institute | 3 | 2024-12-19 | 2026-08-07 |
| PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes, Biopsy, Biospecimen Collection - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Recruiting | City of Hope Medical Center | 21 | 2024-10-09 | 2026-08-21 |
| Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy Bright White Light Therapy, Combination Drug Therapy, Electronic Health Record Review - Advanced Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 210 | 2024-07-09 | 2026-10-07 |
| Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network Training and Education, Educational Intervention, Discussion - Metastatic Prostate Carcinoma, Stage IIIB Prostate Cancer AJCC v8 | Recruiting | Thomas Jefferson University | 30 | 2024-06-03 | 2026-05-15 | |
| Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy Image Guided Biopsy - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 30 | 2024-04-26 | 2026-06-15 |
| FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial Antiandrogen Therapy, Bone Scan, Computed Tomography - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Recruiting | Northwestern University | 125 | 2024-02-18 | 2026-10-08 |
| Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial Supervised Circuit Training - PROSTATE CANCER, Metastatic Prostate Cancer | Not applicable | Recruiting | Dana-Farber Cancer Institute | 80 | 2024-01-01 | 2026-09-10 |
| Access to Genetic Testing in Underserved Patients With Cancer Best Practice, Educational Intervention, Electronic Health Record Review - Breast Carcinoma, Male Breast Carcinoma | Not applicable | Recruiting | University of Southern California | 800 | 2023-10-24 | 2026-03-18 |
| Gallium-68 PSMA-11 PET in Participants With Prostate Cancer Computed Tomography, Gallium Ga 68-labeled PSMA-11, Magnetic Resonance Imaging - Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2022-09-26 | 2024-03-07 | |
| 68Ga-PSMA-11 PET/CT Screening Prior to 177Lu-PSMA-617 Therapy for Patients With Metastatic Castrate Resistant Prostate Cancer Computed Tomography, Gallium Ga 68 Gozetotide, Positron Emission Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 3 | Completed | Mayo Clinic | 163 | 2022-05-09 | 2025-07-18 |
| Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients Cholecalciferol, Quality-of-Life Assessment, Biospecimen Collection - Localized Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8 | Early Phase 1 | Recruiting | Mayo Clinic | 220 | 2021-12-29 | 2026-10-13 |
| Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV Biospecimen Collection, Cabozantinib S-malate, Computed Tomography - Advanced Differentiated Thyroid Gland Carcinoma, Advanced Head and Neck Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 8 | 2021-11-22 | 2026-05-28 |
| 68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer 68Ga-PSMA-11, Positron Emission Tomography (PET) - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Terminated | Thomas Hope | 15 | 2021-09-28 | 2026-05-15 |
| 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Terminated | Rahul Aggarwal | 2 | 2021-08-10 | 2025-05-20 |
| 68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy Computed Tomography, Gallium Ga 68 Gozetotide, Positron Emission Tomography - Biochemically Recurrent Prostate Carcinoma, Metastatic Malignant Neoplasm in the Bone | Phase 2 | Terminated | Jonsson Comprehensive Cancer Center | 22 | 2021-06-16 | 2022-10-21 |
| Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations Biopsy Procedure, Biospecimen Collection, Computed Tomography - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 29 | 2021-04-26 | 2026-08-19 |
| Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer Biospecimen Collection, Questionnaire Administration, Radium Ra 223 Dichloride - Castration-Resistant Prostate Carcinoma, Metastatic Malignant Neoplasm in the Bone | Recruiting | University of Washington | 48 | 2021-04-16 | 2026-10-22 | |
| Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial Cryosurgery, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy - Castration-Resistant Prostate Carcinoma, Metastatic Colorectal Carcinoma | Not applicable | Recruiting | M.D. Anderson Cancer Center | 40 | 2021-03-16 | 2026-04-15 |
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Prostatic Neoplasms (77) · Neoplasm Metastasis (7) · Ovarian Neoplasms (5) · Breast Neoplasms (4) · Carcinoma, Renal Cell (4) · Carcinoma, Transitional Cell (4) · Melanoma (4) · Triple Negative Breast Neoplasms (4) · Colorectal Neoplasms (3) · Lung Neoplasms (3) · Stomach Neoplasms (3) · Carcinoma, Hepatocellular (2) · Carcinoma, Non-Small-Cell Lung (2) · Esophageal Neoplasms (2) · Sarcoma (2)
Genital Diseases (77) · Genital Diseases, Male (77) · Genital Neoplasms, Male (77) · Male Urogenital Diseases (77) · Neoplasms (77) · Neoplasms by Site (77) · Prostatic Diseases (77) · Urogenital Diseases (77) · Urogenital Neoplasms (77) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Pathological Conditions, Signs and Symptoms (8) · Neoplastic Processes (7) · Pathologic Processes (7) · Skin Diseases (7)
Magnetic Resonance Spectroscopy (17) · Abiraterone Acetate (9) · Prednisone (9) · enzalutamide (9) · Specimen Handling (8) · Carboplatin (7) · Docetaxel (6) · Radiation (6) · deltacortene (6) · gallium 68 PSMA-11 (6) · 68Ga-DKFZ-PSMA-11 (5) · apalutamide (5) · prednylidene (5) · Androgen Antagonists (4) · Biopsy (4)
M.D. Anderson Cancer Center (10) · University of Washington (8) · National Cancer Institute (NCI) (7) · Jonsson Comprehensive Cancer Center (6) · Mayo Clinic (4) · Roswell Park Cancer Institute (4) · City of Hope Medical Center (3) · Northwestern University (3) · Thomas Jefferson University (3) · University of Southern California (3) · Barbara Ann Karmanos Cancer Institute (2) · Mamta Parikh (2) · OHSU Knight Cancer Institute (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · University of Utah (2)
United States (72) · China (2) · Puerto Rico (2) · Denmark (1)
Ana Aparicio (3) · Heather H. Cheng (2) · Jeremie Calais (2) · Mamta Parikh (2) · Matthew Rettig (2) · Michael Schweizer (2) · Paul Corn (2) · Rahul Aggarwal, MD (2) · Robert Montgomery (2) · Tanya B Dorff (2) · A P Chen (1) · Adriana Coletta (1) · Alison M Schram (1) · Amy Leader, DrPH, MPH (1) · Amy Leader, DrPh, MPH (1)
PMID 41698328, PMID 27084275, PMID 29027195, PMID 29856824, PMID 29876010, PMID 30700328, PMID 31515154, PMID 33602654, PMID 33989025, PMID 35241087, PMID 35277461, PMID 35405009, PMID 35710085, PMID 36256912, PMID 36351402, PMID 36898948, PMID 37902861, PMID 37922930, PMID 38421243, PMID 38452310, PMID 38867077, PMID 39076107, PMID 39227508, PMID 39420060, PMID 39503807, PMID 40132910, PMID 40139261, PMID 40256659, PMID 40377420, PMID 40591902, PMID 40939237, PMID 41210271, PMID 41315064, PMID 41378786, PMID 41646361, PMID 42847673
P50CA097186 (6), P30CA015704 (5), P30CA014089 (3), P30CA093373 (3), P30CA006973 (2), P30CA022453 (2), P30CA033572 (2), P30CA016056 (1), P30CA016672 (1), P30CA042014 (1), P30CA060553 (1), P30CA072720 (1), P30CA124435 (1), P50CA092131 (1), R01CA130908 (1)