2 recruiting, 1 completed. 3 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Recruiting 2, Completed 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Lymphatic Malformations: new trials by email Literature Review of Lymphatic Malformations trials Research Report on Lymphatic Malformations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome KP-001, Placebo - Venous Malformations, Lymphatic Malformations | Phase 3 | Recruiting | Kaken Pharmaceutical | 150 | 2026-05-13 | 2026-11-12 |
| Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation. Alpelisib, Placebo - Lymphatic Malformations | Phase 2 / Phase 3 | Recruiting | Novartis Pharmaceuticals | 232 | 2023-11-24 | 2026-10-09 |
| Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations picibanil - Lymphatic Malformations | Phase 2 / Phase 3 | Completed | University of Iowa | 150 | 2000-04-01 | 2015-03-25 |
Lymphatic Abnormalities (3) · Lymphangioma (2) · Lymphangioma, Cystic (2) · Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi (1) · Klippel-Trenaunay-Weber Syndrome (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Hemic and Lymphatic Diseases (3) · Lymphatic Diseases (3) · Neoplasm, Lymphatic Tissue (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Angiomatosis (1) · Cardiovascular Diseases (1) · Vascular Diseases (1)
Kaken Pharmaceutical (1) · Novartis Pharmaceuticals (1) · University of Iowa (1)
United States (3) · Argentina (1) · Australia (1) · Belgium (1) · Czechia (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · South Korea (1) · Spain (1) · Switzerland (1) · Taiwan (1) · United Kingdom (1)
Richard J Smith (1)
2023 (1)