8 completed, 2 unknown. 3 Not applicable, 3 Phase 4, 2 Phase 1, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Lipoatrophy: new trials by email Literature Review of Lipoatrophy trials Research Report on Lipoatrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Subdermal Implant "Algeness" Algeness Subdermal Implant (Agarose) - Skin Aging, Facial Wrinkles | Not applicable | Completed | Estelab Clinic | 40 | 2024-06-08 | 2026-06-01 |
| Safety and Efficacy of Injectable Poly-L-Lactic Acid for Volume Loss in the Temples Using Dual Plane Injections Sculptra aesthetic - Lipoatrophy, Aging | Not applicable | Unknown | Sadick Research Group | 20 | 2022-11-01 | 2022-11-08 |
| Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. Berberine, Placebo - Metabolic Syndrome, HIV-1-infection | Phase 3 | Unknown | Hospital Civil de Guadalajara | 40 | 2021-04-01 | 2021-04-26 |
| Beneficial Effect of Insulin Glulisine by Lipoatrophy and Type 1 Diabetes (LAS) Apidra, current insulin - Type 1 Diabetes, Lipoatrophy | Phase 4 | Completed | Kinderkrankenhaus auf der Bult | 14 | 2016-09-01 | 2024-10-15 |
| Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers TAT4 Gel concentration A, TAT4 Gel concentration B, Placebo - Nasolabial Folds, Lipoatrophy | Phase 1 | Completed | Topokine Therapeutics, Inc. | 16 | 2014-10-01 | 2016-01-06 |
| Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells SVF - Lipoatrophy, Aging | Phase 1 | Completed | Antria | 6 | 2013-04-01 | 2015-01-27 |
| Clinical Trial to Assess the Effect of the Change of Efavirenz (EFV) for Lopinavir/Ritonavir (LPV/r) in Lipoatrophy in HIV-infected Patients EFV, LPV/r - HIV Infections, Lipoatrophy | Phase 4 | Completed | Juan A. Arnaiz | 20 | 2009-10-01 | 2014-09-18 |
| Effects of a Uridine Supplement on HIV Infected Adults With Lipoatrophy NucleomaxX, NucleomaxX placebo - HIV Infections, Lipoatrophy | Phase 2 / Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 167 | 2006-09-01 | 2021-11-04 |
| Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir. Different HAART regimens - HIV Associated Lipodystrophy Syndrome., HIV | Phase 4 | Completed | Danish HIV Research Group | 100 | 2004-03-01 | 2005-09-05 |
| Study Comparing Reducing the Dose of Stavudine Versus Switching to Tenofovir in HIV-Infected Patients Receiving Antiretroviral Therapy switching; dose reduction - HIV Infections, Lipoatrophy | Not applicable | Completed | Hospital Clinic of Barcelona | 60 | 2004-01-01 | 2006-10-24 |
Lipodystrophy (10) · HIV Infections (3) · Acquired Immunodeficiency Syndrome (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Dyslipidemias (1) · Glucose Intolerance (1) · HIV-Associated Lipodystrophy Syndrome (1) · Hypercholesterolemia (1) · Metabolic Syndrome (1)
Lipid Metabolism Disorders (10) · Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10) · Skin Diseases (10) · Skin Diseases, Metabolic (10) · Skin and Connective Tissue Diseases (10) · Immune System Diseases (5) · Blood-Borne Infections (4) · Communicable Diseases (4) · Genital Diseases (4) · Immunologic Deficiency Syndromes (4) · Infections (4) · Lentivirus Infections (4) · RNA Virus Infections (4) · Retroviridae Infections (4)
Berberine (1) · Drug Tapering (1) · insulin glulisine (1)
Antria (1) · Danish HIV Research Group (1) · Estelab Clinic (1) · Hospital Civil de Guadalajara (1) · Hospital Clinic of Barcelona (1) · Juan A. Arnaiz (1) · Kinderkrankenhaus auf der Bult (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Sadick Research Group (1) · Topokine Therapeutics, Inc. (1)
United States (3) · Denmark (1) · Puerto Rico (1) · Russia (1) · Spain (1)
Alex Laursen, D.M., DMSc (1) · Ann-Brit E Hansen, M.D. (1) · Court Pedersen, Professor (1) · Grace A. McComsey, MD (1) · Jan Gerstoft, M.D., DMSc (1) · Jose Maria Gatell (1) · Judith A. Aberg, MD (1) · Lars Mathiesen, M.D. DMSc (1) · Niels Obel (1) · Olga Kordonouri, MD (1) · Shahram Rahimian, MD, PhD (1)