2 completed, 2 recruiting, 2 terminated, 1 active not recruiting. 7 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 2, Recruiting 2, Terminated 2, Active not recruiting 1 |
| Phase 1 | 3 | Recruiting 2, Completed 1 |
Follow Leukemia, Acute Lymphoblastic: new trials by email Literature Review of Leukemia, Acute Lymphoblastic trials Research Report on Leukemia, Acute Lymphoblastic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias Autologous HuCD19 ( Anti-CD19)CAR T cells, Cyclophosphamide, Fludarabine - Leukemia, Lymphocytic, Chronic, B-Cell, B-Lymphocytic Leukemia, Chronic | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 132 | 2024-09-03 | 2026-10-16 |
| CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma CART-19 - Leukemia, Acute Lymphoblastic, Lymphoma, Non-Hodgkin | Phase 1 / Phase 2 | Recruiting | University of Sao Paulo | 81 | 2024-03-21 | 2024-12-09 |
| Ponatinib Plus Chemotherapy in Acute Lymphoblastic Leukemia Patients Ponatinib - Chemotherapy, Leukemia, Acute Lymphoblastic | Phase 2 | Active not recruiting | Gruppo Italiano Malattie EMatologiche dell'Adulto | 32 | 2022-10-05 | 2026-03-06 |
| Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe) Fludarabine, Bendamustine Hydrochloride, Busulfan - Leukemia, Acute Lymphoblastic, Myeloid Leukemia, Acute | Phase 2 | Completed | St. Petersburg State Pavlov Medical University | 50 | 2021-01-21 | 2024-05-07 |
| CART19 in Adult Patients With Minimal Residual Disease During Upfront Treatment for ALL CART 19 - Leukemia, Acute Lymphoblastic | Phase 2 | Terminated | University of Pennsylvania | 1 | 2016-10-01 | 2023-06-22 |
| GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia Allogeneic stem cell transplantation, Fludarabine monophosphate, Busulfan - Leukemia, Acute Lymphoblastic, Acute Myeloid Leukemia | Phase 1 / Phase 2 | Completed | St. Petersburg State Pavlov Medical University | 27 | 2016-06-01 | 2020-11-23 |
| Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCT Clofarabine, Cyclophosphamide, Etoposide - Leukemia, Acute Lymphoblastic, Acute Myeloid Leukemia | Phase 2 | Terminated | Medical College of Wisconsin | 6 | 2014-12-08 | 2020-03-09 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (7) · Leukemia, Myeloid, Acute (3) · Leukemia, Biphenotypic, Acute (2) · Immune System Diseases (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Lymphoma (1) · Lymphoma, Non-Hodgkin (1) · Myelodysplastic Syndromes (1) · Myeloproliferative Disorders (1)
Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Immunoproliferative Disorders (7) · Leukemia (7) · Leukemia, Lymphoid (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Immune System Diseases (6) · Leukemia, Myeloid (3) · Bone Marrow Diseases (1) · Chronic Disease (1) · Disease Attributes (1) · Leukemia, B-Cell (1)
Cyclophosphamide (3) · Bendamustine Hydrochloride (2) · Busulfan (2) · fludarabine (2) · CTL019 chimeric antigen receptor (1) · Capsules (1) · Clofarabine (1) · Etoposide (1) · Mycophenolic Acid (1) · Rituximab (1) · Tacrolimus (1) · etoposide phosphate (1) · fludarabine phosphate (1) · ponatinib (1)
St. Petersburg State Pavlov Medical University (2) · Gruppo Italiano Malattie EMatologiche dell'Adulto (1) · Medical College of Wisconsin (1) · National Cancer Institute (NCI) (1) · University of Pennsylvania (1) · University of Sao Paulo (1)
United States (3) · Russia (2) · Brazil (1) · Italy (1)
Boris V. Afanasyev, Professor (1) · Diego V Cle, MD, PhD, MBA (1) · James N Kochenderfer, M.D. (1) · Michael J Burke, MD (1) · Noelle Frey, MD (1) · Sabina Chiaretti (1)