1 completed, 1 recruiting, 1 terminated. 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Lesch-Nyhan Disease: new trials by email Literature Review of Lesch-Nyhan Disease trials Research Report on Lesch-Nyhan Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease Ecopipam, Placebo - Lesch-Nyhan Disease, Self-injurious Behavior | Phase 3 | Terminated | Emalex Biosciences Inc. | 9 | 2012-12-01 | 2024-04-22 |
| Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Rare Disorders, Undiagnosed Disorders | Recruiting | Sanford Health | 20000 | 2010-07-01 | 2026-10-28 | |
| Safety and Tolerability of the D1 Dopamine Receptor Antagonist Ecopipam in Patients With Lesch-Nyhan Disease Ecopipam - Lesch-Nyhan Disease | Phase 1 | Completed | Psyadon Pharma | 5 | 2010-02-01 | 2013-04-18 |
Lesch-Nyhan Syndrome (3) · Self-Injurious Behavior (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1) · Activated PI3K-delta Syndrome (1) · Addison Disease (1) · Alagille Syndrome (1) · Alstrom Syndrome (1) · Amnesia, Transient Global (1) · Aniridia (1) · Aniridia and Absent Patella (1) · Aniridia, Partial, with Unilateral Renal Agenesis and Psychomotor Retardation (1) · Ataxia (1) · Ataxia Neuropathy Spectrum (1)
Brain Diseases (3) · Brain Diseases, Metabolic (3) · Brain Diseases, Metabolic, Inborn (3) · Central Nervous System Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Genetic Diseases, X-Linked (3) · Heredodegenerative Disorders, Nervous System (3) · Intellectual Disability (3) · Metabolic Diseases (3) · Metabolism, Inborn Errors (3) · Nervous System Diseases (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · Nutritional and Metabolic Diseases (3)
ecopipam (2)
Emalex Biosciences Inc. (1) · Psyadon Pharma (1) · Sanford Health (1)
United States (3) · Spain (1)
H J Jinnah, MD (1) · Hyder A Jinnah, MD (1) · William L Nyhan, MD (1)