3 recruiting, 1 unknown. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 3, Unknown 1 |
Follow Histiocytosis, Sinus: new trials by email Literature Review of Histiocytosis, Sinus trials Research Report on Histiocytosis, Sinus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of the RD Regimen(Lenalidomide, Dexamethasone) for Rosai-Dorfman Disease Lenalidomide, Dexamethasone - Rosai-Dorfman Disease | Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 40 | 2025-04-12 | 2025-09-22 |
| Mirdametinib in Histiocytic Disorders Mirdametinib - Langerhans Cell Histiocytosis (LCH), Juvenile Xanthogranuloma (JXG) | Phase 2 | Recruiting | Children's Hospital Medical Center, Cincinnati | 40 | 2024-02-05 | 2026-09-21 |
| Lenalidomide and Dexamethasone for Rosai-Dorfman Disease lenalidomide and dexamethasone - Rosai-Dorfman Disease | Phase 2 | Unknown | Peking Union Medical College Hospital | 16 | 2021-06-08 | 2021-06-16 |
| Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders Cobimetinib - Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma | Phase 2 | Recruiting | Carl Allen | 90 | 2021-04-19 | 2026-10-26 |
Histiocytosis, Langerhans-Cell (2) · Xanthogranuloma, Juvenile (2) · Erdheim-Chester Disease (1) · Histiocytic Disorders, Malignant (1) · Histiocytic Sarcoma (1)
Hemic and Lymphatic Diseases (4) · Histiocytosis (4) · Histiocytosis, Non-Langerhans-Cell (4) · Lymphatic Diseases (4) · Lung Diseases (2) · Lung Diseases, Interstitial (2) · Respiratory Tract Diseases (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Neoplasms (1) · Neoplasms by Histologic Type (1)
Dexamethasone (2) · Lenalidomide (2) · cobimetinib (1) · mirdametinib (1)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Carl Allen (1) · Children's Hospital Medical Center, Cincinnati (1) · Peking Union Medical College Hospital (1)
China (2) · United States (2)
Allison Bartlett, MD (1) · Ashish Kumar, MD, PhD (1) · Carl E Allen, MD, PhD (1) · Dao-bin Zhou (1) · Xinxin XX Cao, doctor (1)