HCV Infection: Clinical Trials

12 trials for HCV Infection, newest first

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12 completed. 12 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 212Completed 12

Follow HCV Infection: new trials by email Literature Review of HCV Infection trials Research Report on HCV Infection

Trials (filtered) newest first · largest first

All 12 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) Infection
AT-527, Daclatasvir - Hepatitis C, Hepatitis C, Chronic
Phase 2CompletedAtea Pharmaceuticals, Inc.102019-06-202020-05-04
Elbasvir (EBR)/Grazoprevir (GZR) in Pediatric Participants With Chronic Hepatitis C Infection (MK-5172-079)
EBR/GZR FDC Tablet, Placebo, Grazoprevir Oral Granules - HCV Infection
Phase 2CompletedMerck Sharp & Dohme LLC572018-01-252023-05-31
Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study
LDV/SOF, RBV - HCV Infection
Phase 2CompletedGilead Sciences1002014-07-012018-11-19
Sofosbuvir Plus Ribavirin, or Ledipasvir/Sofosbuvir in Adults With HCV Infection and Renal Insufficiency
SOF, RBV, LDV/SOF - HCV Infection
Phase 2CompletedGilead Sciences382013-10-072018-08-08
Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination ± Ribavirin in Cirrhotic Subjects With Chronic Genotype 1 HCV Infection
LDV/SOF, RBV, Placebo to match LDV/SOF - HCV Infection
Phase 2CompletedGilead Sciences1552013-10-012018-11-16
Efficacy of PegInterferon-Ribavirin-Boceprevir Therapy in Patients Infected With G1 HCV With Cirrhosis, Awaiting Liver Transplantation
Boceprevir, Peg-Interferon α-2b or Peg-Interferon α-2a, Ribavirin - HCV Infection, Liver Cirrhosis, Experimental
Phase 2CompletedFrench National Agency for Research on AIDS and Viral Hepatitis582012-01-062026-04-07
Efficacy and Safety Study of GS-9256 and GS-9190 Alone and in Combination With Ribavirin for 28 Days in Patients With Chronic Hepatitis C Virus Infection
GS-9256, GS-9190, Ribavirin - HCV Infection
Phase 2CompletedGilead Sciences462010-02-012012-05-31
A Phase 2b, Safety and Efficacy Study of Boceprevir in Patients Coinfected With HIV and Hepatitis C (P05411 AM4)
PegIFN-2b, RBV, Placebo to Boceprevir - HIV Infections, Hepatitis C
Phase 2CompletedMerck Sharp & Dohme LLC992009-11-012017-04-07
Safety, Tolerability, and Antiviral Activity of ANA598 Administered in Combination With Pegylated Interferon and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection
placebo, ANA598, Peginterferon - HCV Infection
Phase 2CompletedHoffmann-La Roche972009-09-012017-03-31
Safety, Tolerability, and Antiviral Activity of 24 or 48 Weeks of GS-9190 in Combination With Peginterferon Alfa 2a and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection
placebo, GS-9190, Peginterferon Alfa 2a - HCV Infection
Phase 2CompletedGilead Sciences2522008-10-012013-11-05
A Follow-up Assessment of Resistance to ABT-333 in Hepatitis C Virus (HCV)-Infected Subjects Who Have Received ABT-333 in ABT-333 Studies
Blood sample collection only, ABT-333 - HCV Infection
Phase 2CompletedAbbVie (prior sponsor, Abbott)352008-08-012015-01-08
Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV
GS-9450, GS-9450 Placebo - HCV Infection
Phase 2CompletedGilead Sciences332008-04-012014-06-19

Narrower conditions

Hepatitis C (12)  ·  Fibrosis (2)  ·  Coinfection (1)  ·  HIV Infections (1)  ·  Hepatitis C, Chronic (1)  ·  Liver Cirrhosis, Experimental (1)

Broader conditions

Blood-Borne Infections (12)  ·  Communicable Diseases (12)  ·  Digestive System Diseases (12)  ·  Flaviviridae Infections (12)  ·  Hepatitis (12)  ·  Hepatitis, Viral, Human (12)  ·  Infections (12)  ·  Liver Diseases (12)  ·  RNA Virus Infections (12)  ·  Virus Diseases (12)  ·  Pathologic Processes (4)  ·  Pathological Conditions, Signs and Symptoms (4)  ·  Chronic Disease (1)  ·  Disease Attributes (1)  ·  Fibrosis (1)

Interventions

Ribavirin (5)  ·  ledipasvir, sofosbuvir drug combination (3)  ·  N-(3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl)-3-(2-((((1,1-dimethylethyl)amino)carbonyl)amino)-3,3-dimethyl-1-oxobutyl)-6,6-dimethyl-3-azabicyclo(3.1.0)hexan-2-carboxamide (2)  ·  peginterferon alfa-2a (2)  ·  peginterferon alfa-2b (2)  ·  tegobuvir (2)  ·  AT-511 (1)  ·  GS-9256 (1)  ·  Sofosbuvir (1)  ·  daclatasvir (1)  ·  dasabuvir (1)  ·  elbasvir (1)  ·  elbasvir-grazoprevir drug combination (1)  ·  grazoprevir (1)  ·  setrobuvir (1)

Sponsors

Gilead Sciences (6)  ·  Merck Sharp & Dohme LLC (2)  ·  AbbVie (prior sponsor, Abbott) (1)  ·  Atea Pharmaceuticals, Inc. (1)  ·  French National Agency for Research on AIDS and Viral Hepatitis (1)  ·  Hoffmann-La Roche (1)

Countries

United States (7)  ·  Puerto Rico (5)  ·  France (4)  ·  Germany (4)  ·  Belgium (3)  ·  Poland (2)  ·  United Kingdom (2)  ·  Australia (1)  ·  Ireland (1)  ·  Mauritius (1)  ·  Moldova (1)  ·  Netherlands (1)  ·  New Zealand (1)  ·  Spain (1)  ·  Sweden (1)

Top investigators

Daniel E Cohen, MD (1)  ·  David Oldach, MD (1)  ·  Didier Samuel, Pr (1)  ·  Juan Betular (1)  ·  Robert H Hyland, DPhil (1)  ·  Steven Knox (1)  ·  Xiao-Jian Zhou, PhD (1)

Results publications

PMID 23768747, PMID 25773757, PMID 25846014, PMID 27554134, PMID 32531259, PMID 36790337

NIH funding

2014 (1), 2015 (1), 2019 (1)