4 active not recruiting. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 4 |
| Phase 1 | 2 | Active not recruiting 2 |
Follow Hamartoma: new trials by email Literature Review of Hamartoma trials Research Report on Hamartoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II Radiprodil - Tuberous Sclerosis Complex, Focal Cortical Dysplasia | Phase 1 / Phase 2 | Active not recruiting | GRIN Therapeutics, Inc. | 30 | 2024-07-10 | 2026-04-01 |
| MK-7075 (Miransertib) in Proteus Syndrome MK-7075 (miransertib) - Proteus Syndrome | Phase 2 | Active not recruiting | National Human Genome Research Institute (NHGRI) | 38 | 2022-05-20 | 2026-07-17 |
| Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study Sirolimus, Placebo - Tuberous Sclerosis Complex, Epilepsy | Phase 2 | Active not recruiting | Darcy Krueger | 64 | 2021-10-13 | 2026-10-29 |
| Feasibility of [11C]Acetate-PET in LAM and TSC [11C]acetate - Lymphangioleiomyomatosis, Tuberous Sclerosis Complex | Phase 1 / Phase 2 | Active not recruiting | Brigham and Women's Hospital | 7 | 2021-08-30 | 2026-01-21 |
Tuberous Sclerosis (3) · Epilepsy (1) · Focal Cortical Dysplasia (1) · Lymphangioleiomyomatosis (1) · Proteus Syndrome (1)
Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Neoplasms (4) · Neoplasms, Multiple Primary (4) · Genetic Diseases, Inborn (3) · Heredodegenerative Disorders, Nervous System (3) · Malformations of Cortical Development (3) · Malformations of Cortical Development, Group I (3) · Neoplastic Syndromes, Hereditary (3) · Nervous System Diseases (3) · Nervous System Malformations (3) · Neurocutaneous Syndromes (3) · Neurodegenerative Diseases (3) · Abnormalities, Multiple (1)
Miransertib (1) · Sirolimus (1) · carbon-11 acetate (1) · radiprodil (1)
Brigham and Women's Hospital (1) · Darcy Krueger (1) · GRIN Therapeutics, Inc. (1) · National Human Genome Research Institute (NHGRI) (1)
United States (3) · Australia (1) · Belgium (1) · Canada (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1) · United Kingdom (1)
Carmen P Priolo, MD PhD (1) · Darcy A Krueger, MD, PhD (1) · Leslie G Biesecker, M.D. (1) · Martina Bebin, MD, MPA (1)
2023 (1)