Gorlin Syndrome: Clinical Trials

2 trials for Gorlin Syndrome, newest first

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2 completed. 2 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 22Completed 2

Follow Gorlin Syndrome: new trials by email Literature Review of Gorlin Syndrome trials Research Report on Gorlin Syndrome

Trials (filtered) newest first · largest first

All 2 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
LDE225, Placebo - Basal Cell Carcinoma, Gorlin Syndrome
Phase 2CompletedNovartis Pharmaceuticals102011-04-012015-10-19
To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)
GDC-0449 - Basal Cell Nevus Syndrome, Gorlin Syndrome
Phase 2CompletedUCSF Benioff Children's Hospital Oakland412009-08-012021-01-11

Narrower conditions

Basal Cell Nevus Syndrome (2)  ·  Carcinoma, Basal Cell (1)

Broader conditions

Abnormalities, Multiple (2)  ·  Bone Cysts (2)  ·  Bone Diseases (2)  ·  Bone Diseases, Developmental (2)  ·  Carcinoma (2)  ·  Congenital Abnormalities (2)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2)  ·  Cysts (2)  ·  Genetic Diseases, Inborn (2)  ·  Jaw Cysts (2)  ·  Jaw Diseases (2)  ·  Musculoskeletal Diseases (2)  ·  Neoplasms (2)  ·  Neoplasms by Histologic Type (2)  ·  Neoplasms, Basal Cell (2)

Interventions

HhAntag691 (1)  ·  sonidegib (1)

Sponsors

Novartis Pharmaceuticals (1)  ·  UCSF Benioff Children's Hospital Oakland (1)

Countries

Austria (1)  ·  Belgium (1)  ·  Canada (1)  ·  Germany (1)  ·  United States (1)

Top investigators

Ervin Epstein, MD (1)

Results publications

PMID 22670904, PMID 24623282, PMID 27838224